PMID: 8582386Sep 1, 1995Paper

At what time are implantable defibrillator shocks delivered? Evidence for individual circadian variance in sudden cardiac death

European Heart Journal
A d'AvilaP Brugada

Abstract

As in myocardial infarction and transient ischaemia, out-of-hospital sudden cardiac death has an increased morning incidence. However, sudden death occurring in hospital is evenly distributed over the 24 h period suggesting that there might be subgroups of patients with atypical circadian patterns of sudden death. Patients who received an implantable defibrillator constitute an ideal group for studies of circadian patterns of sudden death since this generation of devices are able to store the exact time when defibrillation occurred. The distribution of sudden death aborted by the implantable defibrillator was analysed during the 24 h period for 87 presumed appropriate shocks delivered in a group of 22 patients, 18 men and four women, 58.7 +/- 11.9 years old and with a mean left ventricular ejection fraction of 39.4 +/- 17.6%. Each patient received an average of 4.42 +/- 3.04 shocks during a mean follow-up of 9.4 +/- 5.6 months. Apart from a clear tendency for shocks to occur during the morning hours (42% of total shocks), five of 16 patients who received multiple shocks also showed a trend to repeat the shocks around the same period during the day. Our results support the accepted view that changes in autonomic tone in the earl...Continue Reading

Citations

Nov 29, 2014·Journal of Cardiovascular Electrophysiology·Martin H RuwaldValentina Kutyifa
Sep 25, 2008·Pacing and Clinical Electrophysiology : PACE·Thomas J KiernanBernard J Gersh
Jun 9, 2010·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Abhimanyu BeriRanjan Thakur
Jul 14, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Takehiro TsukadaHideaki Yoshino
Jul 13, 2021·Journal of Cardiovascular Electrophysiology·Pasquale VergaraAntonio D'Onofrio

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