PMID: 16634362Apr 26, 2006Paper

Atherogenesis in rheumatology

Lupus
Sander I van LeuvenErik S G Stroes

Abstract

Atherosclerosis is a chronic inflammatory disorder characterized by immune cell activation, inflammation driven plaque formation and subsequent destabilization. In other disorders of an inflammatory nature, the chronic inflammatory state per se has been linked to acceleration of the atherosclerotic process which is underlined by an increased incidence of cardiovascular disease (CVD) in disorders such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and antiphopholipid (Hughes) syndrome (APS). In addition to systemic inflammation, additional mechanisms have been put forward that are more specific for the pathophysiology of the individual chronic inflammatory disorders.

References

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Citations

Aug 28, 2013·Current Treatment Options in Cardiovascular Medicine·Mahesh J Patel, Michael A Blazing
Nov 20, 2012·Current Opinion in Lipidology·Fleur M van der ValkErik S G Stroes
Nov 12, 2010·Annals of the Rheumatic Diseases·Sander I van LeuvenAmy S Major
Oct 18, 2008·Journal of Translational Medicine·Elizabeth A DiBlasio-SmithEdward R LaVallie
Apr 3, 2010·The Open Cardiovascular Medicine Journal·Giuseppe Cocco, Armen Yuri Gasparyan
Oct 12, 2010·Journal of Biomedicine & Biotechnology·Chary López-PedreraMaria José Cuadrado
Jul 30, 2008·Current Rheumatology Reports·Amr H Sawalha, Susan Kovats
Jul 1, 2007·Current Opinion in HIV and AIDS·Sander I van LeuvenErik S G Stroes
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