PMID: 8613610Mar 15, 1996Paper

Atheroma morphology and distribution in proximal left anterior descending coronary artery: in vivo observations

Journal of the American College of Cardiology
B J KimuraA N DeMaria

Abstract

This study sought to examine, in vivo, the shape and position of atheroma in the proximal left anterior descending coronary artery. The prevalence, shape and location of atheromas involving the proximal left anterior descending artery have implications regarding the role of disturbed shear forces in the genesis of atherosclerosis. However, no data are available regarding in vivo findings or advanced disease. Forty-two consecutive high quality intravascular ultrasound images were examined from patients with atherosclerotic disease in the proximal left anterior descending artery just distal to the left main bifurcation. Lesion percent area stenosis and maximal, minimal and flow divider intimal-medial thickness were measured at the region immediately after the circumflex takeoff. The angle formed by the midpoint of the flow divider, the human center of gravity and the maximal plaque thickness were determined. Eccentricity of vessel wall atheroma was observed such that the maximal wall thickness (1.42 +/- 0.50 mm [mean +/- SD]) differed significantly from minimal wall thickness (0.17 +/- 0.098 mm). Further, the region of vessel wall manifesting maximal thickness was greater than the flow divider thickness (0.26 +/- 0.16 mm). Maxima...Continue Reading

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Citations

May 5, 2011·Herz·I IakovouC Di Mario
Oct 10, 2006·The International Journal of Cardiovascular Imaging·Gastón A Rodriguez-GranilloAlfredo E Rodriguez
Apr 25, 2012·Australasian Physical & Engineering Sciences in Medicine·Thanapong ChaichanaJames Jewkes
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Oct 5, 2010·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Fernando AlfonsoJaime Dutary
Oct 5, 2010·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Seung Hwan HanAmir Lerman
Jan 24, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Tadayuki YakushijiMasahiko Ochiai
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