PMID: 8586335Oct 30, 1995Paper

Atherosclerosis in alcoholics

Forensic Science International : Synergy
J L Thomsen

Abstract

A cohort of alcoholics who underwent a medico-legal autopsy during a 5-year period was compared with non-alcoholic controls who did not differ from the alcoholics in selection criteria. The degree of atherosclerosis in the coronary arteries and the aorta was examined. Alcoholic men and old women had a significantly lower degree of atherosclerosis in the coronary arteries, while the opposite was found in young women. In the aorta there was no significant difference in the degree of atherosclerosis between alcoholics and controls in men. Alcoholic women generally had a lower degree of atherosclerosis in the aorta. The so-called U-shaped curve for the relationship between the daily alcohol intake and atherosclerosis is described together with some of the investigations on which it is based. There is much positive evidence for the U-shaped curve, although a causal association has not been proven as yet. The present results indicate a complex relationship, in which different confounding factors are likely to play a role.

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Citations

Apr 30, 1999·Proceedings of the Association of American Physicians·S Zakhari, E Gordis
Jan 22, 2015·Journal of Thrombosis and Thrombolysis·Bengt ZöllerKristina Sundquist
Mar 9, 2018·Digestive Diseases and Sciences·Karen V DanielsenSøren Møller
Jun 28, 2014·International Journal of High Risk Behaviors & Addiction·Sergei V Jargin
May 29, 2010·American Journal of Physiology. Gastrointestinal and Liver Physiology·James C RussellSpencer D Proctor
Jun 26, 1998·British Journal of Pharmacology·J D McKendrickM W Radomski

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