PMID: 14740074Jan 24, 2004Paper

Atherosclerosis in type 2 diabetes mellitus: the role of insulin resistance

Journal of Cardiovascular Pharmacology and Therapeutics
Karol E WatsonGary Matson


Type 2 diabetes mellitus is associated with a marked increase in the risk of atherosclerotic diseases, including coronary heart disease, peripheral arterial disease, and cerebrovascular disease. Insulin resistance is a key factor in the pathogenesis of type 2 diabetes mellitus. Insulin resistance and its attendant metabolic abnormalities may cause much of the increased cardiovascular risk of type 2 diabetes mellitus. Among the abnormalities associated with insulin resistance are dyslipidemia, hypertension, systemic inflammation, and a prothrombotic state. This review discusses the role that each of these disorders plays in the cardiovascular risk of type 2 diabetes mellitus.


Oct 20, 1979·British Medical Journal·J H FullerY Stirling
Jan 1, 1992·Journal of Cardiovascular Pharmacology·R A DeFronzo
Jun 1, 1991·The Journal of Clinical Investigation·E A AndersonA L Mark
Jan 1, 1995·Clinical and Experimental Hypertension : CHE·M S MuntzelA L Mark
Mar 1, 1994·Diabetes·P KarhapääM Laakso
Jul 1, 1993·The Journal of Clinical Investigation·G M ReavenR M Krauss
Jan 1, 1993·Metabolism: Clinical and Experimental·S YoshiokaH Horikoshi
Sep 26, 1997·The Journal of Clinical Investigation·E FerranniniG Mingrone
Oct 6, 1997·Endocrinology and Metabolism Clinics of North America·R R Henry
Apr 4, 1998·The American Journal of Cardiology·R M Krauss
Jan 14, 1999·The New England Journal of Medicine·R Ross
May 5, 1999·Diabetic Medicine : a Journal of the British Diabetic Association·C Day
Jul 27, 1999·The American Journal of Cardiology·W A Hsueh, R E Law
Jul 27, 1999·The American Journal of Cardiology·K Osei
Dec 16, 2000·Arteriosclerosis, Thrombosis, and Vascular Biology·Y ChenD J Schneider
Dec 21, 2000·Current Atherosclerosis Reports·H R Superko
Mar 2, 2002·Journal of Diabetes and Its Complications·Mariella Trovati, Giovanni Anfossi
Apr 12, 2002·Diabetes Research and Clinical Practice·Yoh MiyashitaHitoshi Watanabe
Oct 16, 2002·Current Cardiology Reports·Annaswamy Raji, Jorge Plutzky
Mar 20, 2003·Current Diabetes Reports·James B Meigs
Mar 20, 2003·Journal of the American College of Cardiology·Prediman K Shah
Apr 30, 2003·Diabetes Care·Zachary T Bloomgarden
May 2, 2003·Current Hypertension Reports·Brent M Egan
Jul 18, 2003·Current Diabetes Reports·Eyal Sivan, Guenther Boden
Sep 25, 1954·Journal of the American Medical Association·L G ROWNTREE, R J POPPITI

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