PMID: 14740074Jan 24, 2004Paper

Atherosclerosis in type 2 diabetes mellitus: the role of insulin resistance

Journal of Cardiovascular Pharmacology and Therapeutics
Karol E WatsonGary Matson

Abstract

Type 2 diabetes mellitus is associated with a marked increase in the risk of atherosclerotic diseases, including coronary heart disease, peripheral arterial disease, and cerebrovascular disease. Insulin resistance is a key factor in the pathogenesis of type 2 diabetes mellitus. Insulin resistance and its attendant metabolic abnormalities may cause much of the increased cardiovascular risk of type 2 diabetes mellitus. Among the abnormalities associated with insulin resistance are dyslipidemia, hypertension, systemic inflammation, and a prothrombotic state. This review discusses the role that each of these disorders plays in the cardiovascular risk of type 2 diabetes mellitus.

References

Oct 20, 1979·British Medical Journal·J H FullerY Stirling
Jan 1, 1992·Journal of Cardiovascular Pharmacology·R A DeFronzo
Jun 1, 1991·The Journal of Clinical Investigation·E A AndersonA L Mark
Jan 1, 1995·Clinical and Experimental Hypertension : CHE·M S MuntzelA L Mark
Mar 1, 1994·Diabetes·P KarhapääM Laakso
Jul 1, 1993·The Journal of Clinical Investigation·G M ReavenR M Krauss
Jan 1, 1993·Metabolism: Clinical and Experimental·S YoshiokaH Horikoshi
Sep 26, 1997·The Journal of Clinical Investigation·E FerranniniG Mingrone
Oct 6, 1997·Endocrinology and Metabolism Clinics of North America·R R Henry
Apr 4, 1998·The American Journal of Cardiology·R M Krauss
Jan 14, 1999·The New England Journal of Medicine·R Ross
May 5, 1999·Diabetic Medicine : a Journal of the British Diabetic Association·C Day
Jul 27, 1999·The American Journal of Cardiology·W A Hsueh, R E Law
Jul 27, 1999·The American Journal of Cardiology·K Osei
Dec 16, 2000·Arteriosclerosis, Thrombosis, and Vascular Biology·Y ChenD J Schneider
Dec 21, 2000·Current Atherosclerosis Reports·H R Superko
Mar 2, 2002·Journal of Diabetes and Its Complications·Mariella Trovati, Giovanni Anfossi
Apr 12, 2002·Diabetes Research and Clinical Practice·Yoh MiyashitaHitoshi Watanabe
Oct 16, 2002·Current Cardiology Reports·Annaswamy Raji, Jorge Plutzky
Mar 20, 2003·Current Diabetes Reports·James B Meigs
Mar 20, 2003·Journal of the American College of Cardiology·Prediman K Shah
Apr 30, 2003·Diabetes Care·Zachary T Bloomgarden
May 2, 2003·Current Hypertension Reports·Brent M Egan
Jul 18, 2003·Current Diabetes Reports·Eyal Sivan, Guenther Boden
Sep 25, 1954·Journal of the American Medical Association·L G ROWNTREE, R J POPPITI

❮ Previous
Next ❯

Citations

Sep 11, 2009·Cephalalgia : an International Journal of Headache·H-J GruberM Truschnig-Wilders
Sep 16, 2010·Physiological Genomics·Cameron Rink, Savita Khanna
Jul 18, 2008·Clinical and Experimental Hypertension : CHE·Alireza EsteghamatiAbdul Reza Esteghamati
May 22, 2010·Annals of Medicine·Christopher P F Marinangeli, Peter J H Jones
Aug 27, 2013·The American Journal of Cardiology·Gamze AslanHaldun Muderrisoglu
Mar 2, 2010·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Sherifa A HamedNagia M Mahmoud
Jun 13, 2009·Best Practice & Research. Clinical Endocrinology & Metabolism·Debabrata Mukherjee
Apr 25, 2012·Pain Practice : the Official Journal of World Institute of Pain·Fahri Halit BesirŞeyma Ozdem
Sep 21, 2005·Medical Hypotheses·S YamagishiM Takeuchi
Jul 21, 2009·Journal of Diabetes and Its Complications·Deovina N Jordan, James L Jordan
Mar 19, 2011·American Journal of Hypertension·Abdul Hye Khan, John D Imig
Jul 22, 2005·Cephalalgia : an International Journal of Headache·I RaineroL Pinessi
Dec 19, 2017·Cephalalgia : an International Journal of Headache·Ippazio Cosimo AntonazzoKjetil Bjornevik
Jul 24, 2004·American Journal of Physiology. Heart and Circulatory Physiology·David FultonDavid W Stepp
Nov 7, 2007·Circulation·Carrie L WelchAlan R Tall
Dec 4, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Daming ZhuangAviv Hassid
Jun 23, 2005·The Journal of Biological Chemistry·Louis RagoliaYoshihiro Urade
Nov 25, 2005·Journal of Cardiovascular Pharmacology·Fabrice M A C MartensTon J Rabelink
Jun 9, 2020·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Anastasia OtamasRamzi A Ajjan
Oct 6, 2020·Frontiers in Physiology·Josh FosterGeorge Havenith
Jun 3, 2021·Nutrients·Kathryn Dowis, Simran Banga
Jun 10, 2011·Journal of Agricultural and Food Chemistry·Chi-Hao WuGow-Chin Yen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.