PMID: 29753613DOI: 10.1016/j.tem.2018.04.007May 14, 2018Paper
Atherosclerosis Is an Epigenetic Disease
Trends in Endocrinology and Metabolism : TEM
Suowen XuZheng Gen Jin
Abstract
Atherosclerosis is a chronic inflammatory and lipid-depository disease that eventually leads to acute cardiovascular events. Emerging evidence supports that epigenetic processes such as DNA methylation, histone modification, and noncoding RNAs play an important role in plaque progression and vulnerability, highlighting the therapeutic potential of epigenetic drugs in cardiovascular therapeutics.
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