PMID: 9538305Apr 16, 1998Paper

Atherosclerotic coronary lesions with inadequate compensatory enlargement have smaller plaque and vessel volumes: observations with three dimensional intravascular ultrasound in vivo

Heart
C von BirgelenP J de Feyter

Abstract

To compare vessel, lumen, and plaque volumes in atherosclerotic coronary lesions with inadequate compensatory enlargement versus lesions with adequate compensatory enlargement. 35 angiographically significant coronary lesions were examined by intravascular ultrasound (IVUS) during motorised transducer pullback. Segments 20 mm in length were analysed using a validated automated three dimensional analysis system. IVUS was used to classify lesions as having inadequate (group I) or adequate (group II) compensatory enlargement. There was no significant difference in quantitative angiographic measurements and the IVUS minimum lumen cross sectional area between groups I (n = 15) and II (n = 20). In group I, the vessel cross sectional area was 13.3 (3.0) mm2 at the lesion site and 14.4 (3.6) mm2 at the distal reference (p < 0.01), whereas in group II it was 17.5 (5.6) mm2 at the lesion site and 14.0 (6.0) mm2 at the distal reference (p < 0.001). Vessel and plaque cross sectional areas were significantly smaller in group I than in group II (13.3 (3.0) v 17.5 (5.6) mm2, p < 0.01; and 10.9 (2.8) v 15.2 (4.9) mm2; p < 0.005). Similarly, vessel and plaque volume were smaller in group I (291.0 (61.0) v 353.7 (110.0) mm3, and 177.5 (48.4) v 2...Continue Reading

References

Jan 1, 1989·International Journal of Cardiac Imaging·R I KitneyK Straughan
Jul 1, 1985·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·M L ArmstrongD J Piegors
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Citations

Mar 22, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Mounir W Z Basalus
Nov 25, 2004·International Journal of Cardiology·Lisette Okkels JensenTorben Haghfelt
Mar 5, 2004·Journal of the American College of Cardiology·Stephan AchenbachWerner G Daniel
Aug 27, 2005·Nature Clinical Practice. Cardiovascular Medicine·C J SlagerP W Serruys
Feb 28, 2002·Circulation·Amanda M VarnavaMichael J Davies
Dec 7, 2018·Bioinformatics·Andrew PartonSteven Watterson

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