Atherosclerotic Risk and Statin Use Among Patients With Peripheral Artery Disease

Journal of the American College of Cardiology
Lisandro D ColantonioMichael E Farkouh

Abstract

Peripheral artery disease (PAD) is associated with increased risk for atherosclerotic cardiovascular disease (ASCVD) events. The goal of this study was to compare the risk for ASCVD events and the use of statins among patients with PAD versus those with coronary heart disease (CHD) or cerebrovascular disease. The authors conducted a retrospective cohort study of adults age ≥19 years with commercial or Medicare health insurance who had a history of PAD, CHD, or cerebrovascular disease on December 31, 2014. Patients were followed for ASCVD events comprising CHD, cerebrovascular disease, and PAD events until December 31, 2017. Among 943,232 patients included in the analysis, the age-standardized ASCVD event rate per 1,000 person-years for those with a history of 1, 2, and 3 conditions including PAD, CHD, and cerebrovascular disease was 40.8 (95% confidence interval [CI]: 40.3 to 41.3), 68.9 (95% CI: 67.9 to 70.0), and 119.5 (95% CI: 117.0 to 122.0), respectively. The ASCVD event rate among patients with PAD only, CHD only, and cerebrovascular disease only was 34.7 (95% CI: 33.2 to 36.2), 42.2 (95% CI: 41.5 to 42.8), and 38.9 (95% CI: 37.6 to 40.1), respectively. Among patients with PAD and CHD, with PAD and cerebrovascular disease...Continue Reading

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Citations

Dec 21, 2020·Journal of Clinical Lipidology·Kaylee B CrockettLisandro D Colantonio
Apr 7, 2021·Journal of the American Heart Association·Catherine G DeringtonAdam P Bress
Jun 11, 2021·Circulation Research·Aaron W Aday, Kunihiro Matsushita
Jun 19, 2021·Journal of the American College of Cardiology·Connie N HessMarc P Bonaca
Jun 19, 2021·Journal of the American College of Cardiology·Eric A SecemskyAnna K Krawisz
Jul 18, 2020·Journal of the American College of Cardiology·Marc P Bonaca, Connie N Hess
Nov 3, 2021·Scientific Reports·Hyangkyoung KimYong-Pil Cho

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