Atmospheric and room temperature plasma (ARTP) as a new powerful mutagenesis tool

Applied Microbiology and Biotechnology
Xue ZhangCheng-Yu Bao

Abstract

Developing rapid and diverse microbial mutation tool is of importance to strain modification. In this review, a new mutagenesis method for microbial mutation breeding using the radio-frequency atmospheric-pressure glow discharge (RF APGD) plasma jets is summarized. Based on the experimental study, the helium RF APGD plasma jet has been found to be able to change the DNA sequences significantly, indicating that the RF APGD plasma jet would be a powerful tool for the microbial mutagenesis with its outstanding features, such as the low and controllable gas temperatures, abundant chemically reactive species, rapid mutation, high operation flexibility, etc. Then, with the RF APGD plasma generator as the core component, a mutation machine named as atmospheric and room temperature plasma (ARTP) mutation system has been developed and successfully employed for the mutation breeding of more than 40 kinds of microorganisms including bacteria, fungi, and microalgae. Finally, the prospect of the ARTP mutagenesis is discussed.

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Citations

Oct 16, 2015·Preparative Biochemistry & Biotechnology·Gong ChengWeiguo Zhang
Jul 17, 2016·Applied Biochemistry and Biotechnology·Liang WangZhonggui Mao
Jul 23, 2016·Bioprocess and Biosystems Engineering·Xiangyun LvYonghong Wang
Jul 3, 2016·Journal of Industrial Microbiology & Biotechnology·Yan WangYanhe Ma
Apr 7, 2018·Applied Microbiology and Biotechnology·Yilin RenGuo-Qiang Chen
May 24, 2018·Nature Communications·Yi WuJef D Boeke
Feb 28, 2019·Recent Patents on Biotechnology·Satya Eswari Jujjavarapu, Swasti Dhagat
May 10, 2019·Biotechnology Journal·Lorena Fernández-CabezónPablo I Nikel
Oct 21, 2019·Applied Microbiology and Biotechnology·Li-Qun JinYu-Guo Zheng
Jan 11, 2020·Applied Microbiology and Biotechnology·Qinghui YuGuoquan Hu
Jul 26, 2017·Letters in Applied Microbiology·W HuJ Chen
Apr 7, 2018·Applied Microbiology and Biotechnology·Zhengming ZhuGuocheng Du
Aug 31, 2018·Biotechnology for Biofuels·Jin JinYingjin Yuan
Nov 14, 2018·Applied Microbiology and Biotechnology·Wei HuJi-Hong Chen
Jan 24, 2019·BioMed Research International·Feng QiXinyi Xu
Feb 26, 2019·Applied Microbiology and Biotechnology·Soo Khim Chan, Theam Soon Lim
Dec 14, 2017·Chembiochem : a European Journal of Chemical Biology·Veeresh Juturu, Jin Chuan Wu

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