Atomic resolution duplex structure of the simplified nucleic acid GNA

Chemical Communications : Chem Comm
Mark K SchlegelEric Meggers

Abstract

Double helix variations of glycol nucleic acids (GNA) are revealed by the atomic resolution crystal structure of a 6mer GNA duplex containing solely Watson-Crick type hydrogen-bonded base pairs.

References

Jan 1, 1992·Methods in Enzymology·R E Dickerson
Aug 1, 1988·Journal of Biomolecular Structure & Dynamics·R Lavery, H Sklenar
Feb 1, 1989·Journal of Biomolecular Structure & Dynamics·R Lavery, H Sklenar
Oct 3, 1999·Nature Structural Biology·M Ortiz-LombardíaM Coll
Oct 17, 2001·Journal of Molecular Biology·W K OlsonH M Berman
Feb 7, 2002·Journal of the American Chemical Society·Ruben DeclercqLuc Van Meervelt
Mar 24, 2005·Journal of the American Chemical Society·Lilu ZhangEric Meggers
Aug 17, 2006·Journal of the American Chemical Society·Martin EgliAlbert Eschenmoser
May 1, 2007·Chembiochem : a European Journal of Chemical Biology·Mark K SchlegelEric Meggers
Jun 6, 2008·Journal of the American Chemical Society·Mark K SchlegelEric Meggers
Jan 9, 2009·Angewandte Chemie·Mark K SchlegelEric Meggers
Jan 22, 2009·Organic & Biomolecular Chemistry·Mark K SchlegelEric Meggers
May 16, 2009·The Journal of Organic Chemistry·Mark K Schlegel, Eric Meggers

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Citations

Feb 27, 2014·Organic & Biomolecular Chemistry·Pengfei LiXinjing Tang
Mar 3, 2011·Organic & Biomolecular Chemistry·Hui ZhouLilu Zhang
Aug 2, 2013·Organic & Biomolecular Chemistry·Vipin KumarVenkitasamy Kesavan
Apr 13, 2010·Current Opinion in Structural Biology·Martin Egli, Pradeep S Pallan
Dec 18, 2015·Nucleic Acids Research·Irina AnosovaMartin Egli
Mar 16, 2011·Chemistry & Biodiversity·Daniele D'AlonzoGiovanni Palumbo
Mar 4, 2014·Bioorganic & Medicinal Chemistry Letters·Qin RenYukio Kitade
Aug 16, 2011·The Journal of Organic Chemistry·Andrew T JohnsonOlaf Wiest
Oct 5, 2010·Journal of the American Chemical Society·Hiroyuki AsanumaHiromu Kashida
Jun 2, 2017·Journal of the American Chemical Society·Mark K SchlegelMuthiah Manoharan
Sep 8, 2010·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·G Ekin Atilla-GokcumenEric Meggers
Oct 12, 2011·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·EnJun GaoYaGuang Sun
Oct 3, 2019·Chemical Communications : Chem Comm·Stéphanie Coantic-CastexPascale Clivio
Sep 10, 2010·Current Protocols in Nucleic Acid Chemistry·Su Zhang, John C Chaput
Dec 11, 2020·Nucleic Acids Research·Asem AlenaizanAnton S Petrov
May 14, 2021·Beilstein Journal of Organic Chemistry·Christopher LicznerChristopher J Wilds
Apr 22, 2010·Accounts of Chemical Research·Eric Meggers, Lilu Zhang
May 18, 2021·Chembiochem : a European Journal of Chemical Biology·Keiji Murayama, Hiroyuki Asanuma
Jan 28, 2011·ACS Chemical Biology·Mostafa I FekryKent S Gates
Jun 30, 2019·Journal of the American Chemical Society·Min LuoPiet Herdewijn

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