Atovaquone-proguanil resistance in imported falciparum malaria in a young child

The Pediatric Infectious Disease Journal
Gregory W RoseAnne E McCarthy

Abstract

We discuss a case of atovaquone-proguanil treatment failure in a child from Mozambique, recently arrived in North America. Four weeks after completing therapy, symptomatic parasitemia recurred, caused by Plasmodium falciparum parasites bearing a Tyr268Ser mutation in cytochrome b. We review the literature concerning atovaquone-proguanil resistance, and emphasize the importance of follow-up and consideration of resistance where patients have relapsed symptoms.

References

May 29, 1999·Antimicrobial Agents and Chemotherapy·I K Srivastava, A B Vaidya
Mar 17, 2001·The Journal of Antimicrobial Chemotherapy·F BarchiesiM A Viviani
Jul 29, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Eli SchwartzKevin C Kain
Jan 16, 2004·Scandinavian Journal of Infectious Diseases·Emmanuel BottieauFrederique Jacobs
Oct 13, 2004·The Journal of Infectious Diseases·Ole WichmannUNKNOWN European Network on Surveillance of Imported Infectious Diseases
Dec 2, 2005·The Journal of Antimicrobial Chemotherapy·Lise MussetJacques Le Bras

❮ Previous
Next ❯

Citations

Sep 16, 2009·Therapeutics and Clinical Risk Management·Luiz Ma CarmargoCélia Rs Garcia
May 17, 2011·La Presse médicale·Laetitia ContentinHai Duong Thanh
Jul 29, 2008·Tropical Medicine & International Health : TM & IH·Jacqueline L DeenArjen Dondorp
Aug 31, 2016·Nature Microbiology·Alan H FairlambAndrew P Waters
Dec 14, 2017·The Journal of Antimicrobial Chemotherapy·Henry M StainesSanjeev Krishna
May 26, 2011·Expert Review of Anti-infective Therapy·Emmanuel BottieauAlfons Van Gompel

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.