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ATP-dependent L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, mycothiol biosynthesis enzyme MshC, is related to class I cysteinyl-tRNA synthetases

Biochemistry

May 30, 2002

Dipti SareenRobert C Fahey

Abstract

Mycothiol is a novel thiol produced only by actinomycetes and is the major low molecular weight thiol in mycobacteria. The mycothiol biosynthetic pathway has been postulated to involve ATP-dependent ligation of L-cysteine (Cys) with 1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranosid...read more

Mentioned in this Paper

CARS gene
Mycobacterium tuberculosis H37Rv
Amino Acyl-tRNA Synthetases
Inositol
MT-TA gene
Ligase
Biosynthetic Pathways
Codon, Initiator
Mycothiol
Genus Mycobacterium
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ATP-dependent L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, mycothiol biosynthesis enzyme MshC, is related to class I cysteinyl-tRNA synthetases

Biochemistry

May 30, 2002

Dipti SareenRobert C Fahey

PMID: 12033919

DOI: 10.1021/bi012212u

Abstract

Mycothiol is a novel thiol produced only by actinomycetes and is the major low molecular weight thiol in mycobacteria. The mycothiol biosynthetic pathway has been postulated to involve ATP-dependent ligation of L-cysteine (Cys) with 1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranosid...read more

Mentioned in this Paper

CARS gene
Mycobacterium tuberculosis H37Rv
Amino Acyl-tRNA Synthetases
Inositol
MT-TA gene
Ligase
Biosynthetic Pathways
Codon, Initiator
Mycothiol
Genus Mycobacterium

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