Atrial fibrillation in heart failure with reduced ejection fraction: a case report of exercise training

European Heart Journal. Case Reports
Guilherme Veiga GuimarãesEdimar Alcides Bocchi

Abstract

Heart failure (HF) and atrial fibrillation (AF) are often concomitant and act in a vicious cycle. Atrial fibrillation is associated with greater functional limitations and increased morbidity and mortality in patients with HF. Moreover, AF associated with HF increases patients' physical inactivity, worsening their clinical condition, and prognosis. Exercise training is safe and has clear benefits in HF. However, these benefits have not been demonstrated when AF is associated with HF. We present the case of a 57-year-old man with permanent AF and HF with reduced ejection fraction, who underwent 12 weeks of exercise training that included cardiopulmonary exercise testing, neuromuscular sympathetic activity (NMSA), and muscle blood flow (MBF) before and after training. Exercise training was shown to have a potential benefit in reducing the activity of the sympathetic nerve and increasing muscle blood flow, as well as increasing VO2peak and decreasing the VE/VCO2 slope in a patient with AF associated with HF with reduced ejection fraction. These results may indicate favourable clinical implications in this group of patients.

References

Jun 28, 2008·International Journal of Cardiology·Antonio C P BarrettoCarlos E Negrão
Jul 29, 2008·Arquivos brasileiros de cardiologia·Guilherme Veiga GuimarãesEdimar Alcides Bocchi
Apr 9, 2009·JAMA : the Journal of the American Medical Association·Christopher M O'ConnorUNKNOWN HF-ACTION Investigators
Aug 29, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Vitor Oliveira CarvalhoGuilherme Veiga Guimarães
Mar 31, 2011·Arquivos brasileiros de cardiologia·Guilherme Veiga GuimarãesEdimar Alcides Bocchi
Jun 15, 2011·Arquivos brasileiros de cardiologia·Juliana Fernanda Canhadas BelliGuilherme Veiga Guimarães
Jul 30, 2011·Journal of the American College of Cardiology·Jill Downing, Gary J Balady
Apr 1, 2017·Journal of the American College of Cardiology·Nancy LuoRobert J Mentz
Sep 1, 2017·Journal of the American College of Cardiology·Sandeep PrabhuPeter M Kistler
Feb 1, 2018·The New England Journal of Medicine·Nassir F MarroucheUNKNOWN CASTLE-AF Investigators

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