Atrial Fibrillation in Patients With Left Ventricular Assist Devices: Incidence, Predictors, and Clinical Outcomes

JACC. Clinical Electrophysiology
Kathleen T HickeyAngelo B Biviano

Abstract

This study sought to determine the prevalence of atrial fibrillation (AF) and its association with cardiac outcomes in patients with left ventricular assist devices (LVADs). LVADs are pivotal treatments for end-stage heart failure and a critical bridge to heart transplantation. Medical records of 249 consecutive patients who received an LVAD at Columbia University Medical Center were reviewed. Patient demographics, clinical variables, medications, and outcomes were recorded. Descriptive statistics were generated, and multivariable logistic regression was performed to assess the independent association of clinical variables with the presence of AF. Overall, AF was documented in 80 patients (32%) following LVAD placement. Before LVAD placement, 182 patients had no history of AF, whereas 67 patients had documented AF. Among these 67 patients, 56 (84%) continued to have AF following LVAD placement; 24 patients without a history of AF (13%) developed AF after LVAD placement. Patients manifesting AF after LVAD placement were more likely to have had AF before LVAD insertion (p < 0.001). There were no significant differences in risk of stroke or death for patients with AF before or following LVAD insertion. AF is common in patients wit...Continue Reading

Citations

Jun 8, 2018·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Veraprapas KittipibulNapatt Kanjanahattakij
Jul 19, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·David PeddeEvgenij V Potapov
Mar 19, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Andreas GoetteUNKNOWN ESC Scientific Document Group
Aug 14, 2020·Journal of the American Heart Association·Zak LoringJonathan P Piccini
Feb 26, 2020·Current Opinion in Cardiology·Cevher Ozcan, Amrish Deshmukh
Mar 31, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Maria J Ruiz-CanoMichiel Morshuis

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