Atrial natriuretic factor: sodium transport in human erythrocytes

Clinical Science
N C TrippodoA A MacPhee

Abstract

The effect of partially purified rate atrial natriuretic factor on sodium efflux from sodium-loaded human erythrocytes was studied. High molecular weight (10 000-30 000) and low molecular weight (3000-10 000) fractions of atrial extract were prepared by gel filtration; they had natriuretic activity in rats. Neither fraction affected sodium efflux in erythrocytes. The results suggest that atrial natriuretic factor acts in the kidney by mechanisms other than through inhibition of the Na+-K+ exchange pump or the Na+-K+ cotransport system.

Citations

Jan 2, 1987·European Journal of Biochemistry·M CrabosJ F Cloix
Apr 1, 1988·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·V M Buckalew
Mar 5, 1987·The New England Journal of Medicine·G DerayP Meyer

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.