Mar 1, 1979

Atrioventricular conduction in dogs during anesthesia with isoflurane

C D BlittD G Geha


The effects of 1.25, 2.0, and 2.5 MAC isoflurane on atrioventricular conduction were studied by His-bindle electrocardiography during atrial pacing in ten dogs. No effect upon atrioventricular conduction as evidenced by changes in A--H interval (the time of conduction from low right atrium to His-bundle, representing primary AV nodal conduction) was found at these concentrations. Atrial pacing to 200 beats/min did not influence the A--H interval at the three anesthetic concentrations. The stability of cardiac rhythm observed clinically with isoflurane may be related to this lack of effect upon the AV node.

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Mentioned in this Paper

Methyl Ethers
Diastolic Blood Pressure
Left Bundle Branch of His
Cardiac Conduction System
Structure of Atrioventricular Node
Blood Gas Analysis
Electrocardiographic Recorders
Dose-Response Relationship, Drug
Canis familiaris

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