PMID: 10933376Aug 10, 2000Paper

Atrioventricular septal defects diagnosed in fetal life: associated cardiac and extra-cardiac abnormalities and outcome

Journal of the American College of Cardiology
I C HuggonG Sharland

Abstract

We sought to establish the outlook for fetuses diagnosed with atrioventricular septal defect (AVSD) prenatally and its relation to additional cardiac, extracardiac and chromosomal abnormalities. Prediction of likely outcome of AVSD presenting prenatally is complicated by the wide variation in associated features. Computerized records from 14,726 pregnancies referred to a fetal cardiology center were reviewed retrospectively. Pathological reports, postnatal records, follow-up inquiries and review of echocardiographic video recordings supplemented analysis of the records for all those with AVSD. Atrioventricular septal defect was confirmed in 301 fetuses. Eighty-six (39%) of the 218 with known karyotype had trisomy 21, and 21/218 (10%) had other chromosome abnormalities. Right isomerism occurred in 37/301 (12%) fetuses, left isomerism in 62 (20%), mirror image atrial arrangement in 2 (1%), and 200 (67%) had usual arrangement. Atrioventricular septal defect occurred without any other intracardiac abnormality in 155 fetuses (51%). Extracardiac abnormalities and nonkaryotypic syndromes were evident in 40 fetuses (13%, confidence interval [CI] 9.5-17.1%). Uncomplicated cardiac anatomy was significantly associated with the presence of...Continue Reading

References

Mar 1, 1988·British Heart Journal·M V MachadoL D Allan
Nov 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·K BandoR A Hurwitz
Sep 1, 1995·The Annals of Thoracic Surgery·C L BackerV R Zales
Sep 1, 1994·British Journal of Obstetrics and Gynaecology·K H NicolaidesR J Snijders
Nov 1, 1995·The Annals of Thoracic Surgery·E K SimW G Williams
Aug 1, 1996·The Annals of Thoracic Surgery·V Alexi-MeskishviliR Hetzer
Jan 1, 1996·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·J M RedmondB Sethia

❮ Previous
Next ❯

Citations

Feb 15, 2003·The American Journal of Cardiology·Reza S RazaviJohn M Simpson
Nov 22, 2005·Cardiology in the Young·Robert M FreedomRobert H Anderson
Dec 5, 2009·Obstetrics and Gynecology International·Gokhan YıldırımYavuz Ceylan
Aug 25, 2015·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Laura E BriggsAndy Wessels
Nov 10, 2013·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·Donald P Schrope
Dec 26, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Andrea Z BeatonMary T Donofrio
Jan 5, 2010·Taiwanese Journal of Obstetrics & Gynecology·Chih-Ping Chen
Mar 16, 2011·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D PaladiniC Nappi
Apr 25, 2012·American Journal of Medical Genetics. Part a·James R PriestMichael A Portman
Oct 10, 2013·Congenital Heart Disease·Rima S BaderNorman H Silverman
Apr 25, 2007·American Heart Journal·Rachel M WaldLynne E Nield
Feb 24, 2006·The American Journal of Cardiology·Mio TaketazuLisa K Hornberger
Aug 26, 2009·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D PaladiniC Nappi
Sep 28, 2007·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C BergU Gembruch
Jul 14, 2009·Environmental and Molecular Mutagenesis·Ozlem AkinciMutay Aslan
Sep 27, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C BergU Gembruch
Nov 18, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C BergA A Baschat
Dec 6, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Maciej SłodkiUNKNOWN International Prenatal Cardiology Collaboration Group
Jan 17, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Jan PavlicekMarian Kacerovsky
Jul 10, 2007·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A GalindoJ M Velasco
Jul 18, 2018·Echo Research and Practice·Lindsey E Hunter, Anna N Seale
May 31, 2013·Journal of Perinatology : Official Journal of the California Perinatal Association·A HiroseT Matsuishi
Jun 15, 2014·Pediatric Cardiology·Christine E MacCollLynne E Nield
Jun 24, 2005·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Christoph BergUlrich Gembruch
Mar 10, 2001·Cardiology in the Young·A C Cook
Apr 5, 2013·Birth Defects Research. Part A, Clinical and Molecular Teratology·Attila VereczkeyAndrew E Czeizel
Nov 2, 2004·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A MachlittR Chaoui

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Related Papers

Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie
C BergU Gembruch
American Journal of Medical Genetics
M E PierpontA E Lin
Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
C HofstaetterM Hansmann
© 2021 Meta ULC. All rights reserved