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Atropine and/or diazepam therapy protects against soman-induced neural and cardiac pathology

Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology

Aug 1, 1989

John H McDonoughH E Modrow

PMID: 2792594

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Abstract

Toxic doses of the organophosphonate anticholinesterase agent soman can produce neural and cardiac lesions in animals that survive the acute poisoning. The ability of two standard antidote drugs, atropine and diazepam, along with the oxime pralidoxime (2-PAM) Cl, were evaluated for thei...read more

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Drug Combinations
Antidote
Diazepam
Weighing Patient
Medulla Oblongata
Cholinesterase Inhibitors, Reversible
Antidote [EPC]
Bulla
Brain
Plant bulb
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Atropine and/or diazepam therapy protects against soman-induced neural and cardiac pathology

Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology

Aug 1, 1989

John H McDonoughH E Modrow

PMID: 2792594

DOI:

Abstract

Toxic doses of the organophosphonate anticholinesterase agent soman can produce neural and cardiac lesions in animals that survive the acute poisoning. The ability of two standard antidote drugs, atropine and diazepam, along with the oxime pralidoxime (2-PAM) Cl, were evaluated for thei...read more

Mentioned in this Paper

Drug Combinations
Antidote
Diazepam
Weighing Patient
Medulla Oblongata

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Paper Details
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  • Citations72
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  • Citations72
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