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Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform

Cell

Oct 31, 2019

Eytan HerzigWarner C. Greene

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Abstract

Current approaches to reducing the latent HIV reservoir entail first reactivating virus-containing cells to become visible to the immune system. A critical second step is killing these cells to reduce reservoir size. Endogenous cytotoxic T-lymphocytes (CTLs) may not be adequate because ...read more

Mentioned in this Paper

Blood
HIV Infections
Spleen
T-Lymphocyte
Cytotoxic T-Lymphocytes
CD4 Positive T Lymphocytes
Virus
Adaptation
Size
Antibodies, Neutralizing
163
14
3
65
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Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform

Cell

Oct 31, 2019

Eytan HerzigWarner C. Greene

PMID: 31668804

DOI: 10.1016/j.cell.2019.10.002

Abstract

Current approaches to reducing the latent HIV reservoir entail first reactivating virus-containing cells to become visible to the immune system. A critical second step is killing these cells to reduce reservoir size. Endogenous cytotoxic T-lymphocytes (CTLs) may not be adequate because ...read more

Mentioned in this Paper

Blood
HIV Infections
Spleen
T-Lymphocyte
Cytotoxic T-Lymphocytes
163
14
3
65

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