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ATTEC: a potential new approach to target proteinopathies

Autophagy

Nov 7, 2019

Zhaoyang LiBo-Xun Lu

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Abstract

Many diseases are caused by aberrant accumulation of certain proteins that are misfolded and cytotoxic, and lowering the level of these proteins provides promising treatment strategies for these diseases. We hypothesized that compounds that interact with both the disease-causing protein...read more

Mentioned in this Paper

Huntington Disease
Treatment Protocols
Polyglutamine
Neurodegenerative Disorders
Cytotoxicity
Mutant
Huntington gene
Autophagic Membrane Disassembly
Small Molecule
Microarray Analysis
2
1
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ATTEC: a potential new approach to target proteinopathies

Autophagy

Nov 7, 2019

Zhaoyang LiBo-Xun Lu

PMID: 31690177

DOI: 10.1080/15548627.2019.1688556

Abstract

Many diseases are caused by aberrant accumulation of certain proteins that are misfolded and cytotoxic, and lowering the level of these proteins provides promising treatment strategies for these diseases. We hypothesized that compounds that interact with both the disease-causing protein...read more

Mentioned in this Paper

Huntington Disease
Treatment Protocols
Polyglutamine
Neurodegenerative Disorders
Cytotoxicity
2
1

Similar Papers Found In These Feeds

Paper Details
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