Attention and normalization circuits in macaque V1

The European Journal of Neuroscience
M SanayeiA Thiele

Abstract

Attention affects neuronal processing and improves behavioural performance. In extrastriate visual cortex these effects have been explained by normalization models, which assume that attention influences the circuit that mediates surround suppression. While normalization models have been able to explain attentional effects, their validity has rarely been tested against alternative models. Here we investigate how attention and surround/mask stimuli affect neuronal firing rates and orientation tuning in macaque V1. Surround/mask stimuli provide an estimate to what extent V1 neurons are affected by normalization, which was compared against effects of spatial top down attention. For some attention/surround effect comparisons, the strength of attentional modulation was correlated with the strength of surround modulation, suggesting that attention and surround/mask stimulation (i.e. normalization) might use a common mechanism. To explore this in detail, we fitted multiplicative and additive models of attention to our data. In one class of models, attention contributed to normalization mechanisms, whereas in a different class of models it did not. Model selection based on Akaike's and on Bayesian information criteria demonstrated that...Continue Reading

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Citations

Jul 1, 2016·Journal of Neurophysiology·Douglas A RuffMarlene R Cohen
Jan 10, 2018·Frontiers in Neural Circuits·Jose L HerreroAlexander Thiele
Oct 20, 2015·Nature Neuroscience·Jalal K BaruniC Daniel Salzman
Nov 25, 2020·Proceedings of the National Academy of Sciences of the United States of America·Douglas A RuffMarlene R Cohen
Dec 15, 2020·Vision Research·Ambra CiavarelliClara Casco
Mar 17, 2021·Proceedings of the National Academy of Sciences of the United States of America·Demetrio FerroAlexander Thiele

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