Attention deficits in depression: an electrophysiological marker

Neuroreport
F el MassiouiD Widlöcher

Abstract

EVENT-RELATED POTENTIALS were recorded in young depressed subjects and compared with results from controls. Subjects were required to respond to targets (rare high-frequency sounds) presented to a designated ear, and to ignore targets presented to the non-designated ear as well as standards (frequent low-frequency sounds) presented to either ear. The results confirm those previously obtained with elderly depressed patients, showing the same general profile of electrophysiological and behavioural differences, and in particular a substantial reduction of the N200 amplitude in response to attended targets in depressed subjects. It is suggested that the N200 component could be a marker of depression.

Citations

Mar 24, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·T LepistöE T Aronen
Apr 16, 2003·Psychiatry Research·Stefan KaiserMatthias Weisbrod
Mar 18, 2006·Journal of Integrative Neuroscience·Andrew H KempLeanne M Williams
Mar 11, 2006·Journal of Affective Disorders·Alexander Luke SumichMichael Brammer
Oct 7, 2021·Research on Child and Adolescent Psychopathology·Nicholas J SantopetroGreg Hajcak

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