Attenuated heart rate response in REM sleep behavior disorder and Parkinson's disease

Movement Disorders : Official Journal of the Movement Disorder Society
Gertrud Laura SorensenPoul Jennum

Abstract

The objective of this study was to determine whether patients with Parkinson's disease with and without rapid-eye-movement sleep behavior disorder and patients with idiopathic rapid-eye-movement sleep behavior disorder have an attenuated heart rate response to arousals or to leg movements during sleep compared with healthy controls. Fourteen and 16 Parkinson's patients with and without rapid-eye-movement sleep behavior disorder, respectively, 11 idiopathic rapid-eye-movement sleep behavior disorder patients, and 17 control subjects underwent 1 night of polysomnography. The heart rate response associated with arousal or leg movement from all sleep stages was analyzed from 10 heartbeats before the onset of the sleep event to 15 heartbeats following onset of the sleep event. The heart rate reponse to arousals was significantly lower in both parkinsonian groups compared with the control group and the idiopathic rapid-eye-movement sleep behavior disorder group. The heart rate response to leg movement was significantly lower in both Parkinson's groups and in the idiopathic rapid-eye-movement sleep behavior disorder group compared with the control group. The heart rate response for the idiopathic rapid-eye-movement sleep behavior diso...Continue Reading

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Citations

Feb 5, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jose-Alberto PalmaJorge Iriarte
Apr 7, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Julie Anja Engelhard ChristensenHelge Bjarrup Dissing Sorensen
Nov 25, 2017·Nature Reviews. Neurology·Birgit HöglAleksandar Videnovic
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Sep 6, 2017·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Giacomo ChiaroFederica Provini
Jan 8, 2014·Movement Disorders : Official Journal of the Movement Disorder Society·Ellen GelpiTeresa Ribalta
Apr 2, 2014·Journal of Neurology·Luigi Ferini-StrambiJacques Montplaisir
Mar 5, 2015·Movement Disorders : Official Journal of the Movement Disorder Society·Michael SommerauerPhilipp O Valko
Jun 22, 2013·Current Opinion in Neurology·Maria P GiannoccaroGiuseppe Plazzi
Aug 22, 2018·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Paulo BugalhoManuel Salavisa

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