PMID: 7007895Feb 26, 1981Paper

Attenuation in the control of expression of bacterial operons

Nature
C Yanofsky

Abstract

Bacterial operons concerned with the biosynthesis of amino acids are often controlled by a process of attenuation. The translation product of the initial segment of the transcript of each operon is a peptide rich in the amino acid that the particular operon controls. If the amino acid is in short supply translation is stalled at the relevant codons of the transcript long enough for the succeeding segment of the transcript to form secondary structures that allow the transcribing RNA polymerase molecule to proceed through a site that otherwise dictates termination of transcription. This site is the attenuator; the process is attenuation.

References

Jan 1, 1979·Annual Review of Genetics·M Rosenberg, D Court
Jun 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·N W FraserJ E Darnell
Oct 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·G BarryC Squires
Nov 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·D L OxenderC Yanofsky
Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·J F Gardner
Oct 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F Lee, C Yanofsky
Mar 1, 1978·Journal of Bacteriology·G F Miozzari, C Yanofsky
May 15, 1978·Journal of Molecular Biology·G N Bennett, C Yanofsky
Jan 1, 1978·Annual Review of Biochemistry·S Adhya, M Gottesman
Sep 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·G ZurawskiC Yanofsky
Sep 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·P P Di NoceraC B Bruni
Sep 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·W M Barnes
Nov 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·G Miozzari, C Yanofsky
Dec 14, 1978·Nature·G F Miozzari, C Yanofsky
Dec 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·G ZurawskiC Yanofsky
Oct 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·G V StaufferC Yanofsky
Oct 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·R M GemmillJ M Calvo
Dec 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·E B Keller, J M Calvo
Sep 16, 1978·The Veterinary Record·T N Allsup, W R Griffiths
May 15, 1976·Journal of Molecular Biology·C SquiresC Yanofsky
May 15, 1976·Journal of Molecular Biology·L J Korn, C Yanofsky
Feb 15, 1975·Journal of Molecular Biology·C L SquiresC Yanofsky
May 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J P RichardsonC Lowery
Sep 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·S W Artz, J R Broach
May 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·G ZubayJ H Miller
Aug 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·J K Rose, C Yanofsky
Aug 21, 1972·Journal of Molecular Biology·E N Jackson, C Yanofsky
Jul 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·Y ShimizuM Hayashi
Oct 3, 1973·Nature: New Biology·D McGeochD Morse
Sep 15, 1973·Journal of Molecular Biology·S Hiraga, C Yanofsky

❮ Previous
Next ❯

Citations

Mar 1, 1993·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·L BalvayM Y Fiszman
Jan 1, 1983·Molecular & General Genetics : MGG·D R MoserJ L Campbell
Jan 1, 1983·Molecular & General Genetics : MGG·S F Nowlan, E R Kantrowitz
Jul 1, 1987·Molecular & General Genetics : MGG·I DiazC G Kurland
Jan 1, 1984·Molecular & General Genetics : MGG·H KungD H Calhoun
Jan 1, 1983·Molecular & General Genetics : MGG·G Bogosian, R Somerville
Jan 1, 1984·Molecular & General Genetics : MGG·M J SternG F Ames
Jan 1, 1985·Molecular & General Genetics : MGG·T Grundström, S Normark
Jun 1, 1978·Molecular & General Genetics : MGG·I Saint-Girons, D Margarita
Jan 1, 1984·Molecular & General Genetics : MGG·P NiederbergerR Hütter
Jan 1, 1984·Molecular & General Genetics : MGG·J KopelowitzH Engelberg-Kulka
Sep 1, 1986·Somatic Cell and Molecular Genetics·S C GerkenS M Arfin
Mar 8, 2005·Archives of Microbiology·Wade C Winkler
May 1, 2012·Journal of Molecular Evolution·Nikolay Zenkin
Aug 5, 2008·Functional & Integrative Genomics·Julia KrushkalDerek R Lovley
Dec 15, 1983·Journal of Molecular Biology·M SpringerM Grunberg-Manago
Jan 1, 1986·Progress in Biophysics and Molecular Biology·A Wada, A Suyama
May 15, 1984·Biochimica Et Biophysica Acta·M TrudelM Grunberg-Manago
Jan 6, 1992·Biochimica Et Biophysica Acta·D E RancourtV K Walker
Jan 1, 1983·Bio Systems·G A King

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.