Attitude toward prenatal diagnosis for beta-thalassemia major and medical abortion in Southern Iran

Hemoglobin
Mehran KarimiNader Cohan

Abstract

The aim of this study was to evaluate the degree of acceptability of prenatal diagnosis and voluntary termination of pregnancy in case of a fetus affected with beta-thalassemia major (beta-TM) in patients and their parents in Southern Iran. We interviewed 510 parents who had beta-TM children and 254 patients. A questionnaire was used to record information regarding sex, age, parents' and patients' knowledge about prenatal diagnosis, and their decision regarding abortion of an affected fetus. Of 764 participants, 565 (73.9%) knew a little about prenatal diagnosis and 198 (25.9%) had no knowledge at all, while 711 (93%) were in favor of prenatal diagnosis and 53 (6.9%) were not. Specifically, 663 subjects (86.7%) were in favor of early termination of pregnancy in case of an affected fetus, while (13.2%) were not. Compliance with prenatal diagnosis was high, and the main reason for declining was its cost. No particular correlations were found between the size of the household, the education or the economic level, and the request for early termination of pregnancy of an affected fetus. The decision not to have a medical abortion correlated with religious beliefs only.

References

Feb 1, 1994·Human Reproduction·M L PalombaA Cao
Feb 5, 2002·The Journal of Molecular Diagnostics : JMD·Alan R Thornhill, Karen Snow
Nov 15, 2002·International Journal of Hematology·Antonio Cao
Apr 7, 2007·Journal of Pediatric Hematology/oncology·Hassan AbolghasemiHamid Hoorfar
Jul 14, 2007·Journal of Medical Screening·Mehran KarimiAlireza Hashemi
Oct 15, 2009·Hematology/oncology Clinics of North America·Dario Campana

❮ Previous
Next ❯

Citations

May 21, 2011·Blood Reviews·Barbara J Bain
Oct 25, 2012·Journal of Medical Screening·Sezaneh HaghpanahMehran Karimi
Aug 4, 2018·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Adrina ZhongHelen Dimaras
Jul 30, 2011·Hemoglobin·Mohammad Saeid RahiminejadAli Kord Valeshabad
Jan 13, 2021·The Journal of Obstetrics and Gynaecology Research·Amprapha PhaophanSommai Viboonchart

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.