Attitudes toward medication and the clinical variables in schizophrenia: Structural equation models.

Patient Preference and Adherence
Alessandro RossiP Stratta

Abstract

Our study uses data from a large clinical trial to further dissect the contributors attitude toward antipsychotic medication measured with the Drug Attitude Inventory (DAI) in schizophrenia. A total of 227 consecutive outpatients (140 males, 87 females) with schizophrenia or schizoaffective disorder according to DSM-IV criteria were evaluated. Structural equation models (SEM) were used to examine the relationship between attitudes toward medication as measured with the DAI and clinical variables assessed by Positive and Negative Syndrome Scale (PANSS) and Global Assessment of Functioning (GAF). Among four models, the data better fit a model in which attitudes toward medication (DAI-30) was predicted by PANSS Positive and Insight measures, and GAF (goodness-of-fit = 0.99). The data best fit a model where the most complex interaction of insight measures and positive symptoms does predict attitudes toward medication.

References

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Citations

Apr 19, 2011·The Psychiatric Quarterly·Jui-Kang TsaiFor-Wey Lung

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Software Mentioned

SAS Proc CALIS

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