Attitudes Toward Pre-implantation Genetic Diagnosis (PGD) for Genetic Disorders Among Potential Users in Malaysia

Science and Engineering Ethics
Angelina Patrick OlesenLatifah Amin

Abstract

While pre-implantation genetic diagnosis (PGD) is available and legal in Malaysia, there is an ongoing controversy debate about its use. There are few studies available on individuals' attitudes toward PGD, particularly among those who have a genetic disease, or whose children have a genetic disease. To the best of our knowledge, this is, in fact, the first study of its kind in Malaysia. We conducted in-depth interviews, using semi-structured questionnaires, with seven selected potential PGD users regarding their knowledge, attitudes and decisions relating to the use PGD. The criteria for selecting potential PGD users were that they or their children had a genetic disease, and they desired to have another child who would be free of genetic disease. All participants had heard of PGD and five of them were considering its use. The participants' attitudes toward PGD were based on several different considerations that were influenced by various factors. These included: the benefit-risk balance of PGD, personal experiences of having a genetic disease, religious beliefs, personal values and cost. The study's findings suggest that the selected Malaysian participants, as potential PGD users, were supportive but cautious regarding the us...Continue Reading

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Citations

Nov 28, 2017·Omics : a Journal of Integrative Biology·Angeliki BalasopoulouGeorge P Patrinos
May 29, 2020·Journal of Assisted Reproduction and Genetics·Shachar ZuckermanGheona Altarescu
Jun 14, 2017·Science and Engineering Ethics·Alankrita TanejaRitesh G Menezes
May 11, 2021·Asian Bioethics Review·Chee Ying KuekPek San Tay

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