Attitudes Towards Deprescribing Among Older Adults with Limited Life Expectancy and Their Relatives: A Systematic Review.

Drugs & Aging
Alaa BurghleTrine Graabaek

Abstract

Deprescribing is of particular importance in older adults with limited life expectancy since this population group is highly susceptible to the potential harms of inappropriate medications. This systematic review aimed to explore attitudes towards deprescribing among older adults with limited life expectancy and their relatives. A systematic literature review was conducted in the MEDLINE and EMBASE databases from inception to October 2019. Inclusion criteria were studies specifically describing attitudes towards deprescribing among older adults (≥ 65 years) with limited life expectancy and/or their relatives regardless of study type. Results were analyzed, inspired by the Joanna Briggs Institute's method for synthesis of qualitative data. A total of 842 studies were identified and screened; 84 were full-text assessed for eligibility and 7 were ultimately included. Two studies investigated the attitudes of older adults with limited life expectancy and their relatives towards deprescribing of statins and donepezil, respectively, while the five remaining studies related to attitudes towards deprescribing in general. Four main themes were identified: (1) the well-being of older adults with limited life expectancy; (2) involvement o...Continue Reading

References

Aug 2, 2007·The Annals of Pharmacotherapy·Linda Aagaard ThomsenArne Melander
Jul 23, 2009·Annals of Internal Medicine·David MoherUNKNOWN PRISMA Group
Nov 26, 2009·Drugs & Aging·Johanna JyrkkäSirpa Hartikainen
Jan 12, 2012·JAMA : the Journal of the American Medical Association·Lindsey C YourmanAlexander K Smith
Apr 13, 2012·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Lisa M KalischElizabeth E Roughead
Apr 17, 2012·Clinics in Geriatric Medicine·Murthy Gokula, Holly M Holmes
Aug 6, 2013·Drugs & Aging·Emily ReeveMichael D Wiese
Mar 26, 2014·British Journal of Clinical Pharmacology·Emily ReeveMichael D Wiese
Jul 1, 2014·Academic Medicine : Journal of the Association of American Medical Colleges·Bridget C O'BrienDavid A Cook
Aug 1, 2012·Therapeutic Advances in Drug Safety·Sujo AnathhanamJeremy Robson
Mar 24, 2015·JAMA Internal Medicine·Ian A ScottJennifer H Martin
Sep 5, 2015·Current Clinical Pharmacology·Emily ReeveSarah N Hilmer
Dec 17, 2015·Therapeutic Advances in Drug Safety·Doron GarfinkelGulistan Bahat
Feb 7, 2016·Research in Social & Administrative Pharmacy : RSAP·Mona J KalogianisJ Simon Bell
Jun 5, 2016·BMJ : British Medical Journal·Jesse JansenKirsten McCaffery
Jun 9, 2016·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Emily ReeveSarah N Hilmer
Apr 4, 2017·Clinics in Geriatric Medicine·Holly M Holmes, Adam Todd
May 19, 2017·Journal of Palliative Medicine·Jennifer TjiaJon P Furuno
Sep 20, 2018·Palliative Medicine·Kristel PaqueThierry Christiaens
Oct 14, 2018·Journal of the American Geriatrics Society·Wade ThompsonAnton Pottegård
Jan 11, 2019·British Journal of Clinical Pharmacology·Carina LundbyDorthe Susanne Nielsen

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Citations

Jan 14, 2021·Journal of the American Geriatrics Society·Nagham J AilabouniShelly L Gray
Feb 19, 2021·Journal of the American Geriatrics Society·Carina LundbyAnton Pottegård
Aug 3, 2021·International Journal of General Medicine·Harry WuSarah N Hilmer
Apr 22, 2021·The Senior Care Pharmacist·Dee Mangin, Henry Y H Siu
Jan 26, 2022·Family Practice·Katharine A WallisSusan Wells

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