AtU2AF65b functions in abscisic acid mediated flowering via regulating the precursor messenger RNA splicing of ABI5 and FLC in Arabidopsis

The New Phytologist
Feng XiongXiu-Ling Wang

Abstract

In mammalians and yeast, the splicing factor U2AF65/Mud2p functions in precursor messenger RNA (pre-mRNA) processing. Arabidopsis AtU2AF65b encodes a putative U2AF65 but its specific functions in plants are unknown. This paper examines the function of AtU2AF65b as a negative regulator of flowering time in Arabidopsis. We investigated the expression and function of AtU2AF65b in abscisic acid (ABA)-regulated flowering as well as the transcript abundance and pre-mRNA splicing of flowering-related genes in the knock-out mutants of AtU2AF65b. The atu2af65b mutants show early-flowering phenotype under both long-day and short-day conditions. The transcript accumulation of the flowering repressor gene FLOWERING LOCUS C (FLC) is reduced in the shoot apex of atu2af65b, due to both increased intron retention and reduced transcription activation. Reduced transcription of FLC results, at least partially, from the abnormal splicing and reduced transcript abundance of ABSCISIC ACID-INSENSITIVE 5 (ABI5), which encodes an activator of FLC in ABA-regulated flowering signaling. Additionally, the expression of AtU2AF65b is promoted by ABA. Transition to flowering and splicing of FLC and ABI5 in the atu2af65b mutants are compromised during ABA-indu...Continue Reading

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Citations

Sep 2, 2020·Biochemical Society Transactions·Paola PunzoGiorgia Batelli
Jan 11, 2020·Frontiers in Plant Science·Hao-Dong QiXiu-Ling Wang
Jan 18, 2020·BMC Plant Biology·Long WangFeng Yu
Jul 24, 2020·International Journal of Molecular Sciences·Victor P Bulgakov, Tatiana V Avramenko
May 28, 2019·Frontiers in Plant Science·Hyo-Young ParkJeong-Kook Kim
Oct 13, 2019·Journal of Experimental Botany·Yu-Yi WangXiu-Ling Wang
Dec 19, 2020·Frontiers in Plant Science·Keh Chien LeeJeong-Kook Kim

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