Atypical antipsychotics for the treatment of delirious elders

Journal of the American Medical Directors Association
Lauren B OzboltRobert M Kaiser

Abstract

Delirium occurs frequently in hospitalized patients and is reported to occur at a rate of 10% to 40% in hospitalized elderly patients. The gold standard of treatment is to treat the underlying cause of delirium and use high-potency antipsychotics such as haloperidol to target the behavioral disturbances. Since the development of atypical antipsychotics, many psychiatric conditions that were previously only treatable using high-potency antipsychotics may now be managed with the atypical agents. This review will examine the current literature on atypical antipsychotics and summarize the results from published trials in order to evaluate the efficacy and potential benefits of atypical antipsychotics for the treatment of delirium in the elderly population. A search of the published literature was conducted using MEDLINE and PubMed. The PubMed search was limited to articles that were (1) written in the English language, (2) focused on human subjects above age 65, and (3) were in the format of review articles, randomized controlled trials (RCTs), clinical trials, or meta-analyses. The initial PubMed search was conducted in March 2006 with follow-up investigations in April 2006 and July 2007. Risperidone, the most thoroughly studied a...Continue Reading

References

Jul 1, 1997·The Journal of Clinical Psychiatry·C A ZarateM Tohen
Mar 4, 1999·The New England Journal of Medicine·S K InouyeL M Cooney
Jul 19, 2001·BMJ : British Medical Journal·N Tabet, R Howard
Sep 14, 2001·Psychiatry and Clinical Neurosciences·K S KimT Jun
Nov 3, 2001·The American Journal of Psychiatry·A H Glassman, J T Bigger
Jun 21, 2002·Psychosomatics·Thomas L Schwartz, Prakash S Masand
Jun 21, 2002·Psychosomatics·William BreitbartChristopher Gibson
Mar 19, 2003·Journal of Geriatric Psychiatry and Neurology·Kye Y KimDebra Gropper
Sep 6, 2003·Age and Ageing·Wendy NeilJohn Wattis
Dec 9, 2003·The Journal of Clinical Psychiatry·Yukiya SasakiTsukasa Koyama
Dec 20, 2003·Intensive Care Medicine·Yoanna K SkrobikStewart B Gottfried
Mar 12, 2004·Primary Care Companion to the Journal of Clinical Psychiatry·Steven D. Targum
May 28, 2004·The Journal of Clinical Psychiatry·Dinesh MittalHenry A Nasrallah
Jun 1, 2004·The American Journal of Psychiatry·Nathan HerrmannKrista L Lanctôt
Jul 3, 2004·Psychosomatics·Chang-Su Han, Yong-Ku Kim
Jan 26, 2005·BMJ : British Medical Journal·Sudeep S GillMuhammad Mamdani
Mar 16, 2005·Psychosomatics·James A Bourgeois, Donald M Hilty
Oct 20, 2005·JAMA : the Journal of the American Medical Association·Lon S SchneiderPhilip Insel
Dec 2, 2005·The New England Journal of Medicine·Philip S WangM Alan Brookhart
Mar 3, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Kaisu H PitkäläReijo S Tilvis
Jun 9, 2006·The New England Journal of Medicine·Enrique Anton, Juan Marti
May 3, 2007·Psychiatry and Clinical Neurosciences·Shingo MiyajiHitoshi Miyaoka
Jun 16, 2007·Journal of the American Medical Directors Association·Joseph H FlahertyThomas Edes

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Citations

Jun 26, 2010·Der Nervenarzt·F Jessen, A Spottke
Feb 5, 2009·Zeitschrift für Gerontologie und Geriatrie·Manfred Gogol
Feb 6, 2009·Japanese Journal of Clinical Oncology·Ryuichi SagawaToshiaki A Furukawa
Oct 7, 2010·Psychiatry and Clinical Neurosciences·Hidehiro AndohHideo Matsumoto
Oct 14, 2011·Nursing Research and Practice·Joaquim Cerejeira, Elizabeta B Mukaetova-Ladinska
Sep 10, 2013·Journal of the American Medical Directors Association·Jacqueline Vance
Aug 28, 2013·Journal of Electrocardiology·Dorota ZyśkoJacek Nowak
Nov 28, 2012·Clinics in Geriatric Medicine·Jin H Han, Scott T Wilber
Dec 20, 2011·Cirugía española·Nicolás Martínez-VelillaRafael Sánchez-Ostiz
May 27, 2011·Medicina clínica·Nicolás Ignacio Martínez VelillaAlvaro Casas-Herrero
Aug 17, 2010·Emergency Medicine Clinics of North America·Jin H HanE Wesley Ely
Feb 10, 2010·Journal of the American Medical Directors Association·John E Morley
May 6, 2011·Journal of Gerontological Nursing·Sean P ClarkeRima Styra
Oct 22, 2008·Critical Care Clinics·José R Maldonado
Jul 19, 2013·Psychiatry and Clinical Neurosciences·Hee Ryung WangWon-Myong Bahk
Jun 4, 2010·Human Psychopharmacology·Sung-Wan KimJin-Sang Yoon
Feb 3, 2011·American Journal of Alzheimer's Disease and Other Dementias·Vikrant MittalRajesh R Tampi
Oct 9, 2013·Korean journal of anesthesiology·Jun Gwon Choi
Apr 13, 2012·The American Journal of Hospice & Palliative Care·Eric Prommer
Nov 20, 2019·Psychological Medicine·Nicola WarrenDan Siskind
Jun 13, 2012·Deutsches Ärzteblatt International·Stefan LorenzlSoheyl Noachtar
Jan 6, 2017·The Journal of the American Osteopathic Association·Martin M Forsberg

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