Atypical antipsychotics, more than just an antipsychotic

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

Atypical antipsychotics, more than just an antipsychotic

Abstract

References

The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia.

Neonatal ventral hippocampus lesion induces increase in nitric oxide [NO] levels which is attenuated by subchronic haloperidol treatment

Chronic administration of the neurotrophic agent cerebrolysin ameliorates the behavioral and morphological changes induced by neonatal ventral hippocampus lesion in a rat model of schizophrenia.

Clozapine administration reverses behavioral, neuronal, and nitric oxide disturbances in the neonatal ventral hippocampus rat

Juvenile antioxidant treatment prevents adult deficits in a developmental model of schizophrenia

Inflammation in schizophrenia: A question of balance

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

Molecular targets of atypical antipsychotics: From mechanism of action to clinical differences

Exploring the Dendritic Spine Pathology in a Schizophrenia-related Neurodevelopmental Animal Model

Microglia in the developing prefrontal cortex of rats show dynamic changes following neonatal disconnection of the ventral hippocampus

Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning

Citations

The prefrontal cortex as a target for atypical antipsychotics in schizophrenia, lessons of neurodevelopmental animal models.

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