Atypical basal ganglia germinoma presenting as cerebral hemiatrophy: diagnosis and follow-up with 11C-methionine positron emission tomography.

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Jeehun LeeMunhyang Lee

Abstract

Some basal ganglia germinomas are difficult to diagnose in early stage of disease due to vague initial presentation without discernable mass lesion on brain imaging. We performed this study to determine the usefulness of 11C-methionine positron emission tomography (MET PET) for the diagnosis and monitoring of disease activity. MET PET was performed in three consecutive patients; they presented with cerebral hemiatrophy without definite mass lesions on brain image. The maximum standard tracer uptake values (max SUVs) were calculated and used for the quantitative evaluation of the abnormal MET uptake. A pathological diagnosis was made after stereotactic biopsy using MET PET/computed tomography. The max SUVs significantly decreased after treatment. Basal ganglia germinoma should be considered in the differential diagnosis of patients with progressive hemiparesis and hemiatrophy on magnetic resonance imaging. The MET PET was useful for diagnosis, and it can be valuable in evaluation of treatment effects and monitoring for tumor recurrence.

References

Mar 1, 1978·Journal of Neurosurgery·R KwakJ Suzuki
Feb 1, 1990·Neurologia Medico-chirurgica·H KobayashiJ Shinoda
Jan 1, 1990·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·N TamakiH Ito
Oct 8, 1998·Neuroradiology·D I KimG J Hwang
May 18, 1999·Pediatric Neurology·E LiuS L Pomeroy
Feb 28, 2002·Acta neurochirurgica·C H KimD G Kim
Mar 17, 2004·World Journal of Urology·Maria De Santis, Jörg Pont
Jul 5, 2007·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·S SartoriG Perilongo
Sep 29, 2007·International Journal of Radiation Oncology, Biology, Physics·Pawinee MahasittiwatHirohiko Tsujii
Oct 25, 2007·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Tarun SinghalJoseph Mantil
Nov 17, 2007·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·David J CoopeKarl Herholz
Dec 14, 2007·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Songji ZhaoNagara Tamaki

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Citations

Feb 26, 2013·Journal of Neurosurgery. Pediatrics·Megha MadhukarMark S Dias
Nov 26, 2013·Annals of Nuclear Medicine·Yoshiyuki OkochiShinji Naganawa
Feb 18, 2016·Pediatric Radiology·So Mi LeeSun Kyoung You
Mar 15, 2016·Frontiers in Oncology·Amarnath Challapalli, Eric O Aboagye
Mar 22, 2015·Clinical Neuroradiology·C J MaurerH Urbach
Aug 8, 2018·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ai Peng TanKshitij Mankad
Mar 20, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Nobuyuki KawaiTakashi Tamiya
Jan 21, 2010·Journal of Neuro-oncology·Ji Hoon PhiKyu-Chang Wang
Sep 28, 2013·Journal of Pediatric Hematology/oncology·Winnie Wan-Yee TsoGodfrey Chi-Fung Chan
Jul 3, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ji Hoon PhiKyu-Chang Wang
Mar 6, 2019·Oxford Medical Case Reports·Eike SteidlNiklas Schäfer
Apr 1, 2016·Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko·A N KonovalovM V Ryzhova

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