Atypical polypoid adenomyomas progressed to endometrial endometrioid adenocarcinomas

Archives of Gynecology and Obstetrics
Hong Kai Zhang, Wei Dong Chen

Abstract

Atypical polypoid adenomyoma (APA) is an uncommon uterine tumor which is composed of atypical endometrial glands and cellular smooth-muscle stroma. At present APA is categorized as a benign lesion and treated conservatively in the literatures. However, there are also several cases reported that progressed to endometrial endometrioid adenocarcinoma (EEC) till now. Here, we present two more rare cases of APA that may have undergone progression to EEC. Two patients who had APA 6 and 4 years ago, respectively, and had ECC were reported. The history of the two patients and the literatures were retrospectively reviewed. The truth that APA may have a chance to progress to carcinoma suggests that APA is at least an indicator lesion for the development of EEC, and highlights that clinicians should carefully monitor the patients, and a meticulous follow-up examination is mandatory.

References

Jan 1, 1987·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·P B Clement, R H Young
Aug 1, 1986·American Journal of Clinical Pathology·R H YoungR E Scully
Jul 1, 1981·The American Journal of Surgical Pathology·M T Mazur
Jul 1, 1995·Histopathology·M FukunagaE Ishikawa
Jan 1, 1996·The American Journal of Surgical Pathology·T A LongacreM R Hendrickson
Jul 1, 1996·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·R A SoslowT A Longacre
Sep 25, 2003·Human Pathology·Shunichiro OtaJaime Prat
Dec 7, 2010·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Ayako HoritaAtsuhiko Sakamoto
Jan 29, 2011·The Journal of Obstetrics and Gynaecology Research·Mami FukudaKaneyuki Kubushiro
Jun 21, 2011·Annals of Diagnostic Pathology·Tadashi Terada

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Citations

Jul 27, 2015·Archives of Gynecology and Obstetrics·Hidetaka NomuraNobuhiro Takeshima
Aug 26, 2015·Journal of Minimally Invasive Gynecology·Athanasios ProtopapasDimitrios Loutradis
Mar 27, 2013·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Qiao-Ying JiangRui-Jin Wu
Aug 11, 2018·The Journal of Obstetrics and Gynaecology Research·Risa NarumiHiroyuki Fujiwara
Jan 20, 2018·Japanese Journal of Clinical Oncology·Hidetaka NomuraNobuhiro Takeshima
Apr 2, 2015·The American Journal of Surgical Pathology·Kristýna NěmejcováPavel Dundr
Nov 10, 2017·The Journal of Obstetrics and Gynaecology Research·Qin ChenBingjian Lu
Apr 3, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Samuel Grindstaff, Natalie Banet
Aug 22, 2020·Pathology, Research and Practice·Antonio TravaglinoLuigi Insabato

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