Atypical presentation of gastrointestinal stromal tumor masquerading as a large duodenal cyst: A case report

International Journal of Surgery Case Reports
Ameet KumarApoorv Singh

Abstract

Gastrointestinal stromal tumors (GIST) are solid tumors. A duodenal GIST masquerading as a cystic lesion has never been reported. We report a large duodenal cyst that finally turned out to be a GIST and was managed without a pancreaticoduodenectomy (PD). A 55 year old lady presented with painful lump in epigastrium. A CT scan revealed a large exophytic cystic lesion from the duodenum with a small solid component. An endoscopy showed a polypoid lesion in the second part of the duodenum adjacent to what looked like a diverticulum. A sleeve duodenal resection, duodeno-duodenostomy and pyloric exclusion was done. The histopathology was duodenal GIST. This case posed diagnostic difficulty as it was thought to be either a duplication cyst or a diverticulum of duodenum. The odd point was the small solid component in it. We considered the possibility of a malignancy arising in these settings, which is has been occasionally reported. To our surprise, it turned out to be a GIST. An extensive literature search yielded only four reports that have reported cystic GISTS, all arising from the stomach or pancreas where they have been mistaken for pseudocysts or even a mucinous cystadenocarcinoma of the pancreas. This is the first report of a c...Continue Reading

References

Jan 10, 2004·Journal of Gastroenterology·Itaru NaitohMakoto Itoh
May 24, 2005·Digestive Diseases and Sciences·Guanghui DingMengchao Wu
Oct 16, 2009·Journal of Medical Case Reports·Ursula PauserAlfred C Feller
Feb 22, 2012·International Journal of Colorectal Disease·Alexander BehamMichael B Ghadimi
Jul 27, 2012·Annals of Surgical Oncology·B SeeligerP Pessaux
Mar 22, 2013·World Journal of Gastrointestinal Surgery·Jens HoeppnerUlrich Theodor Hopt

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