Atypical teratoid/rhabdoid tumour with leptomeningeal dissemination in an adult

Acta neurochirurgica
T KawaguchiT Tominaga

Abstract

A 22-year-old man presented with a rare case of atypical teratoid/rhabdoid tumour (AT/RT). Magnetic resonance imaging showed a left cerebellar mass with leptomeningeal dissemination. Partial resection was performed. Histological examination revealed AT/RT. Postoperatively, whole neuraxis and local irradiation were performed. Three-drug chemotherapy with ifosfamide, cisplatin, and etoposide, and adjuvant intrathecal administration of methotrexate were repeated. Near complete response was achieved, and no tumour recurrence/progression has been noticed during the follow up of 24 months. Intensive radiochemotherapy can successfully control AT/RT, even with leptomeningeal dissemination.

Citations

Nov 7, 2008·Brain Tumor Pathology·Toshitaka SenoKeiji Kawamoto
Dec 25, 2010·Brain Tumor Pathology·Kenta TakahashiShinya Tanaka
Nov 17, 2009·Journal of Neurosurgery·Hidehiro TakeiLauren A Langford
Aug 4, 2011·Journal of Clinical Medicine Research·Nicole A ShonkaMark R Gilbert
Jun 21, 2014·Surgical Neurology International·Satoshi Shitara, Yoshinori Akiyama
Sep 8, 2015·World Neurosurgery·Winona W WuIan F Dunn
Aug 18, 2009·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·G MironeB George
Jul 29, 2010·Neuropathology and Applied Neurobiology·T M SchneiderhanM J Riemenschneider
Mar 25, 2017·The American Journal of Surgical Pathology·Satoshi NakataHideaki Yokoo
Nov 6, 2010·AJNR. American Journal of Neuroradiology·L HanP Wu
Mar 23, 2007·Journal of Neuro-oncology·Elena L ZarovnayaC Harker Rhodes
Mar 29, 2008·Journal of Neuro-oncology·Addisalem T MakuriaMetin Ozdemirli
Jul 21, 2006·Journal of Neuro-oncology·Sarah E SquireKaren J Marcus
Nov 13, 2010·British Journal of Neurosurgery·Alok UmredkarR K Vashista
Dec 14, 2018·Frontiers in Oncology·Vivien ChanSumit Das
Dec 19, 2009·Journal of Neuro-oncology·Bassem El-NabboutAli G Saad
Feb 18, 2021·British Journal of Neurosurgery·Ai Jun PengNi Chen

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