Atypical triad of IgA nephropathy: reversible acute kidney injury, gross hematuria, and severe bilateral flank pain

CEN Case Reports
Susan Kim, Warren Chang

Abstract

Reversible acute kidney injury very rarely complicates the course of immunoglobulin A (IgA) nephropathy. We report an atypical case of reversible acute kidney injury, gross hematuria, and severe bilateral flank pain as the presenting triad of IgA nephropathy. Renal biopsy revealed mesangial IgA deposition without glomerular crescents. The patient's renal dysfunction, mediated by red cell tubular obstruction, interstitial nephritis, and tubular necrosis, resolved without intervention. We conclude that IgA nephropathy should be considered in the differential diagnosis for transient acute kidney injury with gross hematuria, and should be appropriately treated based on known prognostic factors.

References

Sep 1, 1988·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·H S LeeH I Koh
Jun 16, 1999·Kidney International. Supplement·L Nolin, M Courteau
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Eduardo GutiérrezManuel Praga
May 8, 2010·Renal Failure·Yao-Ko Wen, Mei-Ling Chen

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