PMID: 2117990Jun 4, 1990Paper

Audiogenic seizures evoked in DBA/2 mice induce c-fos oncogene expression into subcortical auditory nuclei

Brain Research
G Le Gal La Salle, R Naquet

Abstract

Recently the nuclear proto-oncogene c-fos has been shown to be rapidly and transiently expressed following seizures in many types of epilepsies. Until now, immunohistochemical as well as in situ hybridization studies have reported that the dentate gyrus of the hippocampus and most of the cortical areas were invariably heavily labeled. In order to see whether this distribution was reproduced or not in a model of epilepsy which has been proved to not involve these structures, a study was performed on genetically epilepsy-prone DBA/2 mice. Here we show that following audiogenic seizures, c-fos oncoprotein is not expressed in cortical and limbic structures but rather mapped the subcortical auditory nuclei.

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Citations

Mar 1, 1996·Pharmacology, Biochemistry, and Behavior·N Garcia-CairascoK O Nonaka
Sep 1, 1991·Trends in Pharmacological Sciences·J I Morgan, T Curran
Dec 20, 1993·Behavioural Brain Research·N Garcia-CairascoM C Doretto
May 1, 1996·Brain Research. Molecular Brain Research·N KatoB S McEwen
Jan 20, 1992·Neuroscience Letters·A M Snyder-Keller, M G Pierson
Jul 4, 1994·Neuroscience Letters·S SimlerC Marescaux
Jan 1, 1995·Epilepsy Research·C D ApplegateD T Piekut
Aug 15, 2000·Neuroscience and Biobehavioral Reviews·K C Ross, J R Coleman
Jul 22, 1998·Progress in Neurobiology·C L FaingoldA Riaz
Jan 1, 1997·Brain Research Bulletin·S R BeckettC A Marsden
Aug 1, 1997·Nature Genetics·T J BrennanL H Tecott
Aug 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·M A TeilletN M Le Douarin
Jun 1, 1995·Psychiatry and Clinical Neurosciences·N IshidaB S McEwen
Jan 1, 1993·Epilepsia·H M Reid, R L Collins
Mar 13, 2012·Genes, Brain, and Behavior·S M Goebel-GoodyP J Lombroso
Feb 3, 1999·Annals of the New York Academy of Sciences·L K HeislerL H Tecott
Feb 1, 1995·Italian Journal of Neurological Sciences·M A TeilletR Naquet
Sep 28, 2015·Experimental Neurology·Christopher D MakinsonAndrew Escayg

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