Audiological findings in patients treated with radio- and concomitant chemotherapy for head and neck tumors.

Radiation Oncology
Ana Helena B Dell'AringaAlexandre F Rodrigues

Abstract

To evaluate the functionality of the auditory system in patients who underwent radiotherapy and chemotherapy treatment with cisplatin to treat head and neck tumors. Case series with planned data collection. From May 2007 to May 2008 by the Department of Otorhinolaryngology and the Department of Oncology/Radiotherapy at Faculdade de Medicina de Marília. Audiological evaluation (Pure Tone Audiometry (air and bone conduction), Speech Audiometry, Tympanometry, Acoustic Reflex testing and Distortion Product Otoacoustic Emissions) was performed in 17 patients diagnosed with head and neck neoplasia and treated with chemotherapy, using cisplatin, and radiotherapy. 12 left ears (70.5%) and 11 right ears (64.7%) presented bilateral decreased hearing soon after the treatment for the frequency 1 kHz (mild auditory damage) and for the frequency 8 kHz (more significant auditory damage). Patients with head and neck cancer submitted to the conventional radiotherapy treatment, combined with the chemotherapy with cisplatin, presented a high incidence of decreased hearing by the end of treatment. Strong evidence was observed linking auditory alteration to the amount of radiotherapy treatment.

References

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Citations

Jul 1, 2014·Pediatric Blood & Cancer·Emilia PelevaSam J Daniel
May 14, 2014·The Annals of Otology, Rhinology, and Laryngology·Eleonoor A R TheunissenCharlotte L Zuur
Jul 7, 2020·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Ericka Francislaine Dias CostaCarmen Silvia Passos Lima
Nov 12, 2016·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Abhineet JainD Manjunath
Jan 25, 2017·Journal of Toxicology·Jessica PakenVikash Sewram
Oct 16, 2018·Frontiers in Oncology·Pattarawadee PrayuenyongDavid M Baguley

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Methods Mentioned

BETA
X-ray
irradiate

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