Audiometry as a possible indicator of quinine plasma concentration during treatment of malaria

Transactions of the Royal Society of Tropical Medicine and Hygiene
K K KarlssonL Rombo

Abstract

The spread of chloroquine-resistant malaria has led to a resurgence of quinine in clinical use. One of the well-known side effects of quinine, reversible hearing loss, is closely related to the plasma concentration. We suggest that this hearing effect could be used as an aid in therapy control when quinine drug assay is not available.

References

Aug 14, 1990·Neuroscience Letters·K K Karlsson, A Flock
Jan 1, 1988·European Journal of Clinical Pharmacology·N J White

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Citations

Feb 1, 1992·Parasitology Today·R Steffen, R H Behrens
Apr 28, 2004·Transactions of the Royal Society of Tropical Medicine and Hygiene·Stephen Toovey, Andrew Jamieson
Nov 19, 1997·Progress in Neurobiology·M Ulfendahl
Feb 1, 1992·Australian and New Zealand Journal of Medicine·G C Cook
May 26, 2011·Malaria Journal·Jane AchanUmberto D'Alessandro
Jan 29, 2009·Travel Medicine and Infectious Disease·Stephen Toovey
Apr 2, 2015·Critical Reviews in Analytical Chemistry·Mariusz KluskaWiesław Prukała
Feb 7, 2017·Journal of Drug Targeting·Uday Krishna BaruahGifty M Jojo
Apr 2, 2010·Therapeutic Drug Monitoring·Jackson K MukonzoEleni Aklillu

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