PMID: 11926637Apr 3, 2002Paper

Audit of maternal and fetal outcomes in women treated for glucose intolerance during pregnancy

The Australian & New Zealand Journal of Obstetrics & Gynaecology
H David McIntyreJeremy Oats

Abstract

To determine whether one should aim for glycaemia that is statistically 'normal' or for levels of glycaemia low enough to prevent macrosomia (if such a threshold exists) when glucose intolerance is detected during pregnancy. An audit of pregnancy outcomes in women with impaired glucose tolerance in pregnancy as compared to a local age-matched reference group with normal glucose tolerance. Our study suggests that for most patients, more intensive therapy would not have been justified. Maternal smoking appeared to convey some 'advantages' in terms of neonatal outcomes, with reduction in large-for-gestational-age (LGA) infants and jaundice in babies of impaired glucose tolerance (IGT) mothers. These observations demonstrate the importance of considering risk factors other than GTT results in analysing pregnancy outcomes, while emphasising that 'normalisation' of fetal size should not be our only therapeutic endpoint. Our detailed outcome review allows us to reassure patients with GDM that with current treatment protocols, they should have every expectation of a positive pregnancy outcome.

References

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Citations

Jul 13, 2002·Prenatal Diagnosis
Jan 6, 2012·Journal of Developmental and Behavioral Pediatrics : JDBP·Barbara S KisilevskyC Ann Brown
Mar 4, 2005·BMJ : British Medical Journal·Kirsten Duckitt, Deborah Harrington
Dec 17, 2008·BMC Pregnancy and Childbirth·Eliana M WendlandMaria Inês Schmidt
Feb 4, 2010·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·E Albert Reece
Oct 1, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Rita W Driggers, Ahmet Baschat
Dec 5, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Oded Langer
Jul 10, 2010·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S F WongH D McIntyre
Oct 5, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Ahmed Mohamed MagedDalia Ahmed Hamed
Jul 27, 2005·Diabetes Care·Martin N MontoroThomas A Buchanan
Nov 12, 2016·Reproductive Sciences·Antonio FarinaGeralyn Lambert-Messerlian
Jan 10, 2004·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Daniëlle J JacobsAnnabelle Chan
Feb 26, 2008·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Oded Langer
Jan 13, 2004·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Shell Fean WongMurray Stone
Jun 1, 2017·Reproductive Sciences·Antonio FarinaGeralyn Lambert-Messerlian

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