Abstract
It is widely assumed that damage to the peripheral hearing system is an essential prerequisite for the occurrence of tinnitus. However, previous studies have failed to target tinnitus patients with normal hearing. This study aims to investigate if tinnitus patients with normal audiological presentation demonstrate increased intensity dependence at the selected frequencies. This study applied auditory cortical evoked potential test to investigate nine tinnitus patients with normal audiological presentation and nine age- and sex-matched healthy subjects without tinnitus. Auditory cortical evoked potentials (N1-P2) were elicited from stimuli at four frequencies (4000, 2000, 1000 and 500 Hz) with five intensities (50, 56, 62, 68 and 74 dB nHL). Intensity dependences by latency of N1 and amplitude of N1-P2 were surveyed at midline electrodes. The results showed that the intensity dependence by latency of N1 to the pooled frequencies at three midline electrodes, e.g. Fz, Cz and Pz, revealed non-significant difference. However, significant differences existed in the intensity dependence of amplitude N1-P2 to the pooled frequencies at the Fz and Cz positions. These differences suggested that tinnitus patients tended to respond less to ...Continue Reading
References
Oct 1, 1992·The Laryngoscope·A R MøllerM Yokota
May 1, 1985·Electroencephalography and Clinical Neurophysiology·N B CohnD E Shearer
Jun 1, 1994·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·U HegerlD Mrowinski
Dec 1, 1993·Hearing Research·J AttiasZ Shemesh
Mar 26, 1999·Trends in Neurosciences·J P Rauschecker
Jun 23, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·A NorenaS Chéry-Croze
Jul 10, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M T Carrillo-de-la-Peña
Dec 1, 2000·Acta Oto-laryngologica·H Komiya, J J Eggermont
Jul 27, 2001·Hearing Research·G M GerkenJ J Wiorkowski
Aug 17, 2001·Hearing Research·V DietrichC Pantev
Apr 4, 2002·Neuroreport·Alexander KadnerJaime A Pineda
Jun 28, 2002·Physiological Reviews·Josef Syka
Sep 20, 2002·The New England Journal of Medicine·Alan H LockwoodRobert F Burkard
Sep 19, 2003·Hearing Research·A J Noreña, J J Eggermont
Mar 11, 2004·The European Journal of Neuroscience·Eugen DieschHerta Flor
Apr 20, 2004·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Andreas SchwerdtfegerRüdiger Baltissen
Jul 15, 2005·Brain : a Journal of Neurology·Nathan WeiszThomas Elbert
Citations
Mar 11, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·E HoudayerL Leocani
Nov 12, 2016·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·G Ravikumar, V Ashok Murthy
May 6, 2015·Hearing Research·Larry E RobertsBrandon T Paul
Jul 24, 2013·Neuroscience and Biobehavioral Reviews·Larry E RobertsJos J Eggermont
Apr 20, 2013·Neuroscience and Biobehavioral Reviews·Dirk De RidderBerthold Langguth
May 13, 2020·Journal of Audiology & Otology·Jae-Hun LeeIlyong Park
Mar 3, 2019·Journal of the Association for Research in Otolaryngology : JARO·Thanos TzounopoulosCatherine Palmer