Auditory enhancement of visual phosphene perception: the effect of temporal and spatial factors and of stimulus intensity

Neuroscience Letters
Nadia BologniniLotfi B Merabet

Abstract

Multisensory integration of information from different sensory modalities is an essential component of perception. Neurophysiological studies have revealed that audiovisual interactions occur early in time and even within sensory cortical areas believed to be modality-specific. Here we investigated the effect of auditory stimuli on visual perception of phosphenes induced by transcranial magnetic stimulation (TMS) delivered to the occipital visual cortex. TMS applied at subthreshold intensity led to the perception of phosphenes when coupled with an auditory stimulus presented within close spatiotemporal congruency at the expected retinotopic location of the phosphene percept. The effect was maximal when the auditory stimulus preceded the occipital TMS pulse by 40 ms. Follow-up experiments confirmed a high degree of temporal and spatial specificity of this facilitatory effect. Furthermore, audiovisual facilitation was only present at subthreshold TMS intensity for the phosphenes, suggesting that suboptimal levels of excitability within unisensory cortices may be better suited for enhanced crossmodal interactions. Overall, our findings reveal early auditory-visual interactions due to the enhancement of visual cortical excitability...Continue Reading

References

Jan 1, 1970·Brain : a Journal of Neurology·E G Jones, T P Powell
Jun 18, 1998·Perception & Psychophysics·Charles SpenceJon Driver
Jun 14, 2002·Brain Research. Cognitive Brain Research·Charles E Schroeder, John J Foxe
Sep 27, 2003·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Kathleen S Rockland, Hisayuki Ojima
Mar 31, 2004·Trends in Cognitive Sciences·Marc O Ernst, Heinrich H Bülthoff
May 4, 2005·Trends in Neurosciences·E Macaluso, Jon Driver
Jul 16, 2005·Current Opinion in Neurobiology·Charles E Schroeder, John J Foxe
Sep 2, 2005·Perception & Psychophysics·Matthias GondanBrigitte Röder
Oct 4, 2005·Journal of Cognitive Neuroscience·Wolfgang A Teder-SälejärviSteven A Hillyard
Oct 26, 2005·Neuron·Christoph KayserNikos K Logothetis
Dec 6, 2005·The European Journal of Neuroscience·Céline Cappe, Pascal Barone
May 23, 2006·Trends in Cognitive Sciences·Asif A Ghazanfar, Charles E Schroeder
Jun 27, 2006·Neuropsychologia·A MeienbrockL Muckli
Jul 15, 2006·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·E Macaluso
Feb 23, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Christoph KayserNikos K Logothetis
Apr 13, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ciro Ramos-EstebanezAlvaro Pascual-Leone
Oct 26, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Vincenzo RomeiGregor Thut
Oct 30, 2007·Current Biology : CB·Nadia Bolognini, Angelo Maravita
Feb 28, 2009·PloS One·Anthony D CateDavid L Woods
Oct 17, 2009·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Simone RossiSafety of TMS Consensus Group

Citations

Oct 5, 2013·Experimental Brain Research·Nadia BologniniGiuseppe Vallar
Dec 20, 2012·Journal of Cognitive Neuroscience·Silvia ConventoNadia Bolognini
Jan 23, 2014·Experimental Brain Research·Yung-Hao Yang, Su-Ling Yeh
Nov 19, 2013·Journal of Cognitive Neuroscience·Stephanie Gleiss, Christoph Kayser
Sep 15, 2014·Neural Networks : the Official Journal of the International Neural Network Society·Mauro UrsinoElisa Magosso
Aug 16, 2015·Neuropsychologia·Micah M MurrayPawel J Matusz
May 29, 2013·Annals of the New York Academy of Sciences·Charles Spence
Aug 29, 2013·Human Brain Mapping·Nienke M van AtteveldtCharles E Schroeder
Feb 13, 2014·NeuroImage·Cristiano CuppiniMauro Ursino
Dec 21, 2012·Neuroscience and Biobehavioral Reviews·Nadia BologniniLotfi B Merabet
Feb 20, 2013·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Lucas SpiererMicah M Murray
May 25, 2015·Journal of the Neurological Sciences·Franziska WickmannAndrea Antal
Apr 17, 2012·Current Biology : CB·Vincenzo RomeiGregor Thut
Jul 19, 2013·The Quarterly Journal of Experimental Psychology : QJEP·Alexis D J MakinJayne Pickering
Nov 1, 2013·Psychological Science·Kevin C DieterDuje Tadin
Sep 24, 2018·Reviews in the Neurosciences·Noemi CsászárIstván Bókkon
Mar 19, 2019·Journal of Cognitive Neuroscience·Christopher FassnidgeElliot D Freeman
May 29, 2019·Multisensory Research·Philip SandersGrant Searchfield
Aug 18, 2020·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Elliot D Freeman

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

KIF1A Associated Neurological Disorder

KIF1A associated neurological disorder (KAND) is a rare neurodegenerative condition caused by mutations in the KIF1A gene. KAND may present with a wide range and severity of symptoms including stiff or weak leg muscles, low muscle tone, a lack of muscle coordination and balance, and intellectual disability. Find the latest research on KAND here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.