Auditory resting-state network connectivity in tinnitus: a functional MRI study.

PloS One
A MaudouxAndrea Soddu

Abstract

The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus patients. The aim of this study was to test if functional MRI "resting-state" connectivity patterns in auditory network differ between tinnitus patients and normal controls. Thirteen chronic tinnitus subjects and fifteen age-matched healthy controls were studied on a 3 tesla MRI. Connectivity was investigated using independent component analysis and an automated component selection approach taking into account the spatial and temporal properties of each component. Connectivity in extra-auditory regions such as brainstem, basal ganglia/NAc, cerebellum, parahippocampal, right prefrontal, parietal, and sensorimotor areas was found to be increased in tinnitus subjects. The right primary auditory cortex, left prefrontal, left fusiform gyrus, and bilateral occipital regions showed a decreased connectivity in tinnitus. These results show that there is a modification of cortical and subcortical functional connectivity in tinnitus encompassing attentional, mnemonic, and emotional networks. Our data corroborate the hypothesized implication of non-auditory regions in tinnitus physio...Continue Reading

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References

Jan 1, 1991·Annals of the New York Academy of Sciences·N E Morton
Sep 1, 1965·Journal of Psychosomatic Research·A W Beard
May 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S D FormanD C Noll
Mar 1, 1995·Cerebral Cortex·S K Rosahl, R T Knight
Feb 1, 1993·British Journal of Audiology·P J Jastreboff, J W Hazell
Oct 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B BiswalJ S Hyde
Feb 1, 1996·Archives of Otolaryngology--head & Neck Surgery·C W NewmanJ B Spitzer
Jan 1, 1996·Scandinavian Audiology·R S Hallam
Aug 19, 1999·Hearing Research·F MirzA Gjedde
Jul 27, 2000·Annals of the New York Academy of Sciences·A EngelienD Silbersweig
Sep 3, 2002·Hearing Research·Samuel A ReyesAlan H Lockwood
Apr 9, 2004·Proceedings of the National Academy of Sciences of the United States of America·Michael D GreiciusVinod Menon
Oct 12, 2004·Trends in Neurosciences·Jos J Eggermont, Larry E Roberts
Mar 1, 2005·NeuroImage·Fabrizio EspositoFrancesco Di Salle
Apr 23, 2005·Human Brain Mapping·Augusto PetacchiJames M Bower
Aug 10, 2005·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Christian F BeckmannStephen M Smith
Sep 29, 2005·Neuroreport·Yasuhiro OsakiTakeshi Kubo
Dec 24, 2005·Proceedings of the National Academy of Sciences of the United States of America·M D HunterP W R Woodruff
Sep 2, 2006·Proceedings of the National Academy of Sciences of the United States of America·J S DamoiseauxC F Beckmann
Nov 23, 2006·Acta Oto-laryngologica. Supplementum·Dirk De RidderPaul Van De Heyning
Feb 9, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Nathan WeiszThomas Elbert
Mar 25, 2008·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Tobias KleinjungBerthold Langguth
Apr 24, 2008·PloS One·Martijn van den HeuvelHilleke Hulshoff Pol
Apr 15, 2009·Hearing Research·Peyman AdjamianDeborah A Hall
Jul 22, 2009·Proceedings of the National Academy of Sciences of the United States of America·Stephen M SmithChristian F Beckmann
Nov 26, 2009·BMC Biology·Winfried SchleeNathan Weisz
Dec 26, 2009·Brain : a Journal of Neurology·Audrey VanhaudenhuyseMelanie Boly
Jul 14, 2010·Neuron·Josef P RauscheckerMark Mühlau
Aug 1, 1946·Annals of Surgery·J L POOL
Jan 12, 2011·Neuron·Amber M LeaverJosef P Rauschecker
Apr 20, 2011·Proceedings of the National Academy of Sciences of the United States of America·Dirk De RidderBerthold Langguth
Jun 16, 2011·Journal of Cognitive Neuroscience·Angela R LairdPeter T Fox

❮ Previous
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Citations

Jun 4, 2014·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Fedor Panov, Brian Harris Kopell
Jan 11, 2014·PloS One·Martin SchecklmannBerthold Langguth
Feb 12, 2014·PloS One·Maura Regina LaureanoAndrea Parolin Jackowski
Mar 10, 2016·NeuroImage. Clinical·Anusha MohanSven Vanneste
Feb 13, 2016·Nature Reviews. Neurology·Susan E ShoreBerthold Langguth
Feb 3, 2016·Scientific Reports·Anusha MohanSven Vanneste
Oct 20, 2015·Brain Connectivity·Hye Bin YooSven Vanneste
Mar 2, 2016·Scientific Reports·Astrid LehnerBerthold Langguth
May 29, 2015·Scientific Reports·D P SpiegelG D Searchfield
Sep 29, 2015·Trends in Cognitive Sciences·Josef P RauscheckerMarkus Ploner
Nov 21, 2015·AJNR. American Journal of Neuroradiology·N YakuninaE C Nam
Aug 19, 2015·NeuroImage·Bernadet L KlaassensJoop M A van Gerven
Sep 1, 2015·Journal of Neurosurgery·Dirk De RidderSven Vanneste
Jun 29, 2015·Brain : a Journal of Neurology·Athena DemertziSteven Laureys
Sep 17, 2015·Nature Reviews. Neuroscience·Ana Belén ElgoyhenSven Vanneste
Aug 25, 2015·Hearing Research·Amber M LeaverJosef P Rauschecker
Nov 10, 2013·International Journal of Audiology·J DaviesD A Hall
Jun 25, 2015·Frontiers in Neurology·Dirk De RidderRodolfo Llinas
Oct 1, 2014·Cell and Tissue Research·Jos J Eggermont, Larry E Roberts
Jul 16, 2014·Neural Plasticity·Massimo SalviatiGiancarlo Cianfrone
Jul 31, 2013·Hearing Research·Fatima T Husain, Sara A Schmidt
Feb 24, 2015·Neuroscience Letters·Dirk De Ridder, Sven Vanneste
Mar 6, 2015·Frontiers in Neurology·Jos J Eggermont, Peter A Tass
Mar 20, 2015·BioMed Research International·Yu-Chen ChenGao-Jun Teng
Jan 8, 2015·Frontiers in Neurology·Grant D Searchfield
Nov 12, 2014·Frontiers in Neurology·Benjamin D AuerbachRichard J Salvi
Jan 15, 2014·PloS One·Guillermo HorgaEduard Parellada
Jul 28, 2016·Frontiers in Aging Neuroscience·Yu-Chen ChenXindao Yin
Aug 9, 2016·BMC Ear, Nose, and Throat Disorders·Dennis GolmBirgit Kröner-Herwig

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Methods Mentioned

BETA
imaging technique

Software Mentioned

BrainVoyager
Brain Voyager

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