Augmentation in anterior cruciate ligament reconstruction-a histological and biomechanical study on goats

International Orthopaedics
P BumaA Van Kampen

Abstract

We studied reconstruction of the anterior cruciate ligament (ACL) in skeletally mature goats. In one group, the autogenous tissue was augmented with polydioxanone (PDS), the other group had no augmentation. Histological complete incorporation and remodeling of the transplant was found in both groups. The newly formed connective tissues gradually assumed the microscopic properties of the normal ligament. The augmented group showed a delay in remodeling and maturation of the fiber bundles. Mechanically, the PDS-augmented transplants were stronger than the nonaugmented transplants immediately after surgery. During the first 6 weeks, a rapid decrease in strength of the augmented transplants was found, whereas the strength of the nonaugmented group gradually increased. The results of our experiment do not favor augmentation of autografts in reconstruction of the ACL.

References

Aug 1, 1987·The British Journal of Surgery·J WissingJ Jeekel
Jan 1, 1986·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·T J van RensW Kuypers
Nov 1, 1986·The American Journal of Sports Medicine·D AmielW H Akeson
Jan 1, 1995·Archives of Orthopaedic and Trauma Surgery·D TrägerW Tschirner
Jul 1, 1996·Journal of Biomedical Materials Research·K J MargeviciusK Hanselmann
Jun 3, 1998·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·H Tohyama, K Yasuda
May 1, 1999·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·G HehlT Wissmeyer

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Citations

Aug 22, 2009·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Yuki KatoFreddie H Fu
Jan 11, 2007·Tissue Engineering·Michelle Hairfield-SteinPaul Kosnik
Dec 20, 2008·Tissue Engineering. Part B, Reviews·Kadriye Tuzlakoglu, Rui L Reis
Jun 6, 2013·Journal of Biomedical Materials Research. Part a·Natalie L LeongDavid R McAllister
Sep 5, 2015·Journal of Orthopaedic Surgery and Research·Bekir KarakilicElcil Kaya Bicer
Jul 28, 2005·Biomaterials·Cato T Laurencin, Joseph W Freeman
May 10, 2017·JBJS Reviews·Gregory R WaryaszPaul D Fadale
Mar 27, 2018·The American Journal of Sports Medicine·Kwang Il LeeDarryl D D'Lima
May 10, 2007·Expert Review of Medical Devices·Vincenzo GuarinoLuigi Ambrosio
Jun 5, 2018·Applied Bionics and Biomechanics·M MarieswaranDinesh Kalyanasundaram
Jul 28, 2020·Journal of Orthopaedic Surgery·Jared A LombardiHui Xu

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