Augmentation of exercise-induced muscle sympathetic nerve activity during muscle heating

Journal of Applied Physiology
C A Ray, K H Gracey

Abstract

The muscle metabo- and mechanoreflexes have been shown to increase muscle sympathetic nerve activity (MSNA) during exercise. Group III and IV muscle afferents, which are believed to mediate this response, have been shown to be thermosensitive in animals. The purpose of the present study was to evaluate the effect of muscle temperature on MSNA responses during exercise. Eleven subjects performed ischemic isometric handgrip at 30% of maximal voluntary contraction to fatigue, followed by 2 min of postexercise muscle ischemia (PEMI), with and without local heating of the forearm. Local heating of the forearm increased forearm muscle temperature from 34.4 +/- 0.2 to 38.9 +/- 0.3 degree C (P = 0.001). Diastolic and mean arterial pressures were augmented during exercise in the heat. MSNA responses were greater during ischemic handgrip with local heating compared with control (no heating) after the first 30 s. MSNA responses at fatigue were greater during local heating. MSNA increased by 16 +/- 2 and 20 +/- 2 bursts per 30 s for control and heating, respectively (P = 0.03). When expressed as a percent change in total activity (total burst amplitude), MSNA increased 531 +/- 159 and 941 +/- 237% for control and heating, respectively (P =...Continue Reading

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Citations

Oct 9, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Nathan T KuipersChester A Ray
Mar 13, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Jonathan S Cook, Chester A Ray
Mar 30, 2010·Acta Physiologica·C G Crandall, J González-Alonso
Aug 29, 2014·Sports Medicine·Nicole T Vargas, Frank Marino
Oct 11, 2015·The European Journal of Neuroscience·Gothje LautenschlägerHeidrun H Krämer
Sep 27, 2005·Sports Medicine·Chris R Abbiss, Paul B Laursen
Mar 16, 2011·Experimental Physiology·Frank E Marino
Nov 28, 2008·Journal of Applied Physiology·D R Pendergast, C E G Lundgren
Dec 26, 2015·European Journal of Applied Physiology·Timothy A VanHaitsmaAndrea T White
Mar 22, 2020·Experimental Brain Research·Rochelle AckerleyHeidrun H Krämer
Jun 12, 2009·American Journal of Physiology. Renal Physiology·Nathan T KuipersChester A Ray
Feb 15, 2011·European Journal of Applied Physiology·Noriyo TakahashiFumihiro Tajima
Sep 15, 2007·The Journal of Physiology·José González-AlonsoJohn M Johnson
Apr 10, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Tatsuro AmanoNarihiko Kondo
Dec 24, 2010·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·James PearsonJosé González-Alonso
Oct 21, 2016·Journal of Applied Physiology·Jian CuiLawrence I Sinoway
Jun 9, 2017·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Alex LloydGeorge Havenith
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Jun 5, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Alex LloydGeorge Havenith
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Apr 2, 2021·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Jian CuiLawrence I Sinoway

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