Natural killer (NK) cell activity of spleen cells from male CBA/J mice was augmented by a single parenteral injection of MnCl2 administered 1 day prior to testing by in vitro and in vivo isotope release assays. Increased cytotoxic activity was observed in vitro against both NK-sensitive (YAC-1) and NK-resistant (EL-4) target cells. NK activity was also enhanced in normally low (A/J) and intermediately (C57Bl/6J) reactive strains of mice. Augmentation of NK activity by MnCl2 was accompanied by an increase in circulating interferon (IFN) levels.
Calcium antagonists and lipolysis in isolated rat epididymal adipocytes: effects of tetracaine, manganese, cobaltous and lanthanum ions and D600
Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts
The modifying effect of manganese on the enzymic profiles and pathways of carbohydrate metabolism in rat liver and adipose tissue during development
The effect of manganese on lipogenesis, lipolysis, adenosine 3',5' cyclic monophosphate and cyclic nucleotide phosphodiesterase activity in adipocytes from NZY mice
Heavy metal modulation of lymphocyte activities. 1. In vitro effects of heavy metals on primary humoral immune responses
Variation in selectivity of tumor cell cytolysis by murine macrophages, macrophage-like cell lines and NK cells
Factors influencing the phagocytosis, neoplastic transformation, and cytotoxicity of particulate nickel compounds in tissue culture systems
Radioisotope assay for evaluation of in vivo natural cell-mediated resistance of mice to local transplantation of tumor cells
Manganese chloride enhances natural cell-mediated immune effector cell function: effects on macrophages
Selective immunotoxic effects in mice treated with the adenosine deaminase inhibitor 2'-deoxycoformycin
Effects of manganese, calcium, magnesium, and zinc on nickel-induced suppression of murine natural killer cell activity
Immune function in mice exposed to the adenosine deaminase inhibitor 2'-deoxycoformycin during immune system development
Effects of mainstream and environmental tobacco smoke on the immune system in animals and humans: a review
Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy.
Effect of High Dietary Manganese on the Immune Responses of Broilers Following Oral Salmonella typhimurium Inoculation
Cancer Biology: Molecular Imaging
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