Augmentation of prolactin secretion by estrogen in hypogonadal women

The Journal of Clinical Investigation
S S YenT M Siler

Abstract

The effect of estrogen on prolactin (PRL) release and gonadotropin suppression was assessed in six experiments performed on four hypogonadal women. Ethinyl estradiol at a dose of 1 microgram/kg per day induced a significant elevation of serum PRL levels within the 1st wk of treatment. There was a further rise until a plateau was reached in about 3-4 wk to levels of more than 3 times the initial concentration. This was accompanied by a pattern of increased episodic fluctuation. The corresponding serum luteinizing hormone and follicle-stimulating hormone fell progressively during the study period. These data indicate that a positive feedback relationship between estrogen and PRL release exists in humans.

References

Jun 1, 1973·The Journal of Clinical Endocrinology and Metabolism·L S JacobsW H Daughaday
Nov 1, 1973·The Journal of Clinical Endocrinology and Metabolism·J S RakoffS S Yen
Mar 1, 1973·The Journal of Clinical Endocrinology and Metabolism·Y N SinhaW P VanderLaan
Dec 1, 1972·The Journal of Clinical Endocrinology and Metabolism·S S YenR Rebar
Aug 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·P HwangH Friesen
Mar 1, 1970·The Journal of Clinical Endocrinology and Metabolism·S C YenA S Littell
Dec 1, 1968·The Journal of Clinical Endocrinology and Metabolism·S S YenO H Pearson
Nov 1, 1964·Proceedings of the Society for Experimental Biology and Medicine·C S NICOLL, J MEITES

❮ Previous
Next ❯

Citations

Nov 1, 1979·Journal of Microsurgery·L K Page, W J LeMaire
Jan 30, 2007·Breast Cancer Research and Treatment·Gail A GreendaleArun Karlamangla
Oct 1, 1977·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M K JonesG I Dyer
Jul 1, 1983·Journal of Steroid Biochemistry·I M SpitzS Trestian
Jun 1, 1979·Metabolism: Clinical and Experimental·T YamajiT Yanaihara
Jan 1, 1975·European Journal of Obstetrics, Gynecology, and Reproductive Biology·P F TauberH P Schneider
Jan 9, 1992·European Journal of Obstetrics, Gynecology, and Reproductive Biology·C Castelo-BrancoJ González-Merlo
Jan 1, 1979·Pharmacology & Therapeutics. Part B: General & Systematic Pharmacology·M F el-Etreby, K J Gräf
Oct 1, 1978·Molecular and Cellular Endocrinology·E HaugK M Gautvik
Apr 1, 1978·Psychoneuroendocrinology·A E Boyd, S Reichlin
Jan 1, 1988·Psychoneuroendocrinology·N S Whitworth
Jan 29, 1999·Endocrinology and Metabolism Clinics of North America·S S Yen
Apr 1, 1995·Baillière's Clinical Endocrinology and Metabolism·J A Schlechte
Sep 25, 2002·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·P DielG Vollmer
Mar 17, 1977·The New England Journal of Medicine·D L KleinbergA G Frantz
Nov 25, 2003·The New England Journal of Medicine·Janet A Schlechte
Dec 1, 1977·British Journal of Obstetrics and Gynaecology·R J PepperellJ B Brown
Jul 1, 1975·The Journal of Clinical Investigation·M J AubertS L Kaplan
Dec 1, 1979·The Journal of Clinical Investigation·D S CooperF Maloof
Jun 12, 2004·Neurosurgical Focus·James K Liu, William T Couldwell
Jan 1, 1979·Journal of Endocrinological Investigation·A BarbarinoB Matteucci
Oct 1, 1979·Journal of Endocrinological Investigation·M GiustiG Giordano
Oct 1, 1978·Journal of Endocrinological Investigation·P M KicovicS Krempl
Dec 1, 1993·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·V De LeoD Lanzetta
Feb 1, 1997·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·B W HartmannG Söregi
Jul 29, 2009·Climacteric : the Journal of the International Menopause Society·T SathyapalanS L Atkin
Jun 15, 1985·American Journal of Obstetrics and Gynecology·S S YenN S Cetel
Mar 1, 1989·American Journal of Obstetrics and Gynecology·C R ParkerP C MacDonald
Sep 1, 1989·Mayo Clinic Proceedings·B W ScheithauerN Ryan
Feb 1, 1985·Clinics in Endocrinology and Metabolism·K Y HoM O Thorner
Oct 24, 2006·Clinical Endocrinology·A GarasI E Messinis
Apr 15, 1995·Biological Psychiatry·C M HadiganE Hollander
Oct 1, 1977·Metabolism: Clinical and Experimental·K L Cohen
Aug 1, 1980·Metabolism: Clinical and Experimental·M T BuckmanL S Srivastava

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.