Augmentation of screw fixation with injectable calcium sulfate bone cement in ovariectomized rats

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Xiao-Wei YuTing-Ting Tang

Abstract

The objective of this study was to determine the effect of augmenting screw fixation with an injectable calcium sulfate cement (CSC) in the osteoporotic bone of ovariectomized rats. The influence of the calcium sulfate (CS) on bone remodeling and screw anchorage in osteoporotic cancellous bone was systematically investigated using histomorphometric and biomechanical analyses. The femoral condyles of 55 Sprague-Dawley ovariectomized rats were implanted with screw augmented with CS, while the contralateral limb received a nonaugmented screw. At time intervals of 2, 4, 8, 12, and 16 weeks, 11 rats were euthanized. Six pair-matched samples were used for histological analysis, while five pair-matched samples were preserved for biomechanical testing. Histomorphometric data showed that CS augmented screws activated cancellous bone formation, evidenced by a statistically higher (p < 0.05) percentage of osteoid surface at 2, 4, and 8 weeks and a higher rate of bone mineral apposition at 12 weeks compared with nonaugmented screws. The amount of the bone-screw contact at 2, 8, and 12 weeks and of bone ingrowth on the threads at 4 and 8 weeks was greater in the CS group than in the nonaugmented group (p < 0.05), although these parameters i...Continue Reading

References

Jan 1, 1991·Journal of Biomechanics·D R CarterT E Orr
May 1, 1993·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·R V SnydersJ J Delfino
Nov 5, 1997·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·G PecoraJ S Sottosanti
May 1, 1999·Journal of Clinical Periodontology·S R MacNeillP Spencer
Sep 3, 1999·The Orthopedic Clinics of North America·B K TayD S Bradford
Nov 14, 2000·Journal of Biomedical Materials Research·K KawagoeH Yoshikawa
Jan 9, 2001·Hormone Research·E Dennison, C Cooper
Jan 12, 2001·Clinical Orthopaedics and Related Research·C M KellyP T Kim
Nov 27, 2002·International Endodontic Journal·Y MurashimaH Suda
May 21, 2003·Clinical Oral Implants Research·Emeka NkenkeFriedrich Wilhelm Neukam
Mar 1, 1959·American Journal of Surgery·L F PELTIER
Nov 1, 2003·The Spine Journal : Official Journal of the North American Spine Society·Michael T RohmillerDan M Spengler
Nov 13, 2004·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R CurtisN Suhm
Nov 10, 2005·Journal of Biomedical Materials Research. Part a·Christopher L PetersRoy D Bloebaum
Nov 18, 2005·The Spine Journal : Official Journal of the North American Spine Society·Isador H LiebermanMark M Kayanja
Nov 18, 2005·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Kwok Sui LeungPauline Po Yee Lui
Mar 29, 2006·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Hiromi OdaSyuhei Morimoto
Jul 11, 2006·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·V V Välimäki, H T Aro
Jul 11, 2006·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·S Larsson
Sep 27, 2006·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·P von der LindenN Suhm
Apr 20, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Mark A ReynoldsMichael D Rohrer
Jul 10, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Annalisa PalmieriFrancesco Carinci

❮ Previous
Next ❯

Citations

Nov 9, 2012·Journal of Tissue Engineering and Regenerative Medicine·Matilde BongioJohn A Jansen
Mar 26, 2010·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Xi LiuYan Wang
Jun 11, 2010·Journal of Biomaterials Science. Polymer Edition·Yongqiang HeYu Liu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved