Australian Diabetes Screening Study: impaired glucose tolerance and non-insulin-dependent diabetes mellitus

Metabolism: Clinical and Experimental
T A WelbornG Marriott

Abstract

In preventing non-insulin-dependent diabetes mellitus (NIDDM) and its complications, screening high-risk individuals complements public health measures. Our screening instrument for patients of general practitioners was a questionnaire for self-determined high-risk groups plus a laboratory measurement of a random venous plasma glucose level. Collaborating practitioners evaluated 100 consecutive outpatients aged 40 years or older. The questionnaire identified patients with two or more diabetic symptoms or with two or more risk factors, and they were recommended to have their blood tested. For those with a random plasma glucose greater than 5.5 mmol/L, oral glucose tolerance tests (OGTTs) were advised. Of 50,859 subjects completing the study, there were 1,013 cases (2.0%) of new diabetes, 1,704 cases (3.4%) of impaired glucose tolerance (IGT), and 5,508 cases (10.8%) of previously diagnosed diabetes. Symptoms alone were a relatively poor discriminant. Almost all newly identified NIDDM and IGT patients had two or more risk factors for NIDDM. The risk ratios for abnormal glucose tolerance were as follows: high blood pressure, 2.4; overweight, 2.0; and positive family history, 1.7. Selection of cutoff points higher than 5.5 mmol/L w...Continue Reading

Citations

Nov 10, 2000·Diabetic Medicine : a Journal of the British Diabetic Association·B DepczynskiA Keogh
Aug 20, 2003·Diabetic Medicine : a Journal of the British Diabetic Association·S M SmithR G Firth
Mar 25, 2015·Qualitative Health Research·Rizwana KousarPaul Lewandowaski
Jun 27, 2000·Diabetes/metabolism Research and Reviews·S J GriffinN J Wareham
Feb 26, 2000·Diabetic Medicine : a Journal of the British Diabetic Association·B DepczynskiA Keogh
Mar 13, 2008·Journal of General Internal Medicine·David C ZiemerLawrence S Phillips
Oct 29, 2002·Diabetes Care·Deborah J HiltonChristopher M Reid
Apr 9, 2002·The Medical Journal of Australia·Deborah J HiltonChristopher M Reid
Aug 9, 2006·The Medical Journal of Australia·Merlin C ThomasTim H Mathew

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