Auto-aggregation in zoospores of Phytophthora infestans: the cooperative roles of bioconvection and chemotaxis

Journal of the Royal Society, Interface
Andrew I M SavoryFordyce A Davidson

Abstract

Phytophthora infestans is a highly destructive plant pathogen. It was the cause of the infamous Irish potato famine in the nineteenth century and remains to this day a significant global problem with associated costs estimated at $3 billion annually. Key to the success of this pathogen is the dispersal of free-swimming cells called zoospores. A poorly understood aspect of zoospore behaviour is auto-aggregation--the spontaneous formation of large-scale patterns in cell density. Current competing hypotheses suggest that these patterns are formed by one of two distinct mechanisms: chemotaxis and bioconvection. In this paper, we present mathematical and experimental results that together provide strong evidence that auto-aggregation can only result from a combination of these mechanisms, each having a distinct, time-separated role. A better understanding of the underlying infection mechanisms of P. infestans and potentially other Phytophthora species will in the longer term lead to advances in preventative treatment and thus potentially significant savings in socio-economic costs.

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Citations

Jun 12, 2016·Environmental Science & Technology·Rungroch SungthongJose Julio Ortega-Calvo
Jan 27, 2017·PLoS Pathogens·Marie Larousse, Eric Galiana
Aug 8, 2019·Journal of the Royal Society, Interface·Eric GalianaXavier Noblin
May 19, 2017·Molecular Plant Pathology·A R Hardham, Leila M Blackman
Feb 26, 2019·Frontiers in Microbiology·He JiangJianjun Hao
Dec 12, 2020·Computational and Structural Biotechnology Journal·Ilaria BassaniEric Galiana
Apr 7, 2021·Biological Reviews of the Cambridge Philosophical Society·Jonathan AmponsahCalum R Wilson

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